| Weight | 302.349 g/mol |
|---|---|
| Formula | C17H19FN2O2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 7 |
Safinamide (133865-89-1)
Score:
#157 in Neurology
,
#705 in Neuroscience
,
#3140 in Biology
,
#3928 in Chemistry
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- TCI - Safinamide102.00 - 303.00 USD
- Structures of Human Monoamine Oxidase B Complexes with Selective Noncovalent Inhibitors: Safinamide and Coumarin Analogs. (Journal of Medicinal Chemistry, 2007)
- Safinamide From molecular targets to a new anti-Parkinson drug (Neurology, 2006)
- Improvement of motor function in early Parkinson disease by safinamide (Neurology, 2004)
- Randomized trial of safinamide add-on to levodopa in Parkinson's disease with motor fluctuations. (Movement Disorders, 2014)
- Symptom relief in Parkinson disease by safinamide: Biochemical and clinical evidence of efficacy beyond MAO-B inhibition (Neurology, 2006)
- Pharmacokinetics and pharmacodynamics of safinamide, a neuroprotectant with antiparkinsonian and anticonvulsant activity (Pharmacological Research, 2004)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F
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InChIKeyNEMGRZFTLSKBAP-UHFFFAOYSA-N
- Pubchem - Safinamide
- Wikipedia - safinamide
Safinamide (INN; brand name Xadago) is a drug used as an add-on treatment for Parkinson's disease during "off" episodes; it has multiple modes of action, including the inhibition of monoamine oxidase B. It was approved in Europe in February 2015, and in the United States in March 2017.
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