| Weight | 392.406 g/mol |
|---|---|
| Formula | C19H22F2N4O3 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 3 |
sparfloxacin (111542-93-9, 110871-86-8)
Score:
#318 in Microbiology
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#1171 in Physics
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#2668 in Biology
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#3335 in Chemistry
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- Targeting of DNA gyrase in Streptococcus pneumoniae by sparfloxacin: selective targeting of gyrase or topoisomerase IV by quinolones. (Antimicrobial Agents and Chemotherapy, 1997)
- Sparfloxacin-loaded PLGA nanoparticles for sustained ocular drug delivery (Nanomedicine: Nanotechnology, Biology and Medicine, 2010)
- Moxifloxacin, Ofloxacin, Sparfloxacin, and Ciprofloxacin against Mycobacterium tuberculosis: Evaluation of In Vitro and Pharmacodynamic Indices That Best Predict In Vivo Efficacy (Antimicrobial Agents and Chemotherapy, 2007)
- Study of comparative antipneumococcal activities of penicillin G, RP 59500, erythromycin, sparfloxacin, ciprofloxacin, and vancomycin by using time-kill methodology. (Antimicrobial Agents and Chemotherapy, 1994)
- The effect of reserpine, an inhibitor of multidrug efflux pumps, on the in-vitro activities of ciprofloxacin, sparfloxacin and moxifloxacin against clinical isolates of Staphylococcus aureus. (Journal of Antimicrobial Chemotherapy, 1998)
- Synthesis and structure-activity relationships of 5-substituted 6,8-difluoroquinolones, including sparfloxacin, a new quinolone antibacterial agent with improved potency (Journal of Medicinal Chemistry, 1990)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1CN(CC(N1)C)C2=C(C3=C(C(=C2F)N)C(=O)C(=CN3C4CC4)C(=O)O)F
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InChIKeyDZZWHBIBMUVIIW-UHFFFAOYSA-N
- Pubchem - sparfloxacin
- Wikipedia - sparfloxacin
Sparfloxacin (spar FLOX a sin), trade names Spacin in Bangladesh, Zagam and Zagam Respipac, is a fluoroquinolone antibiotic used in the treatment of bacterial infections. It has a controversial safety profile. Zagam is no longer available in the United States.
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sparfloxacin
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