| Weight | 379.366 g/mol |
|---|---|
| Formula | C14H25N3O9 |
| Hydrogen Acceptors | 10 |
| Hydrogen Donors | 8 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 3 |
KASUGAMYCIN
kasugamycin, phosphate salt · kasugamycin monohydrochloride · 3-O-(2-amino-4((carboxyiminomethyl)amino)-2,3,4,6-tetradeoxy-alpha-D-arabino-hexopyranosyl)-D-chiroinositol
19408-46-9, 6980-18-3, 11030-24-3
Score:
#202 in Microbiology
,
#739 in Biochemistry
,
#2038 in Biology
,
#2491 in Chemistry
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- Mechanism of Kasugamycin Resistance in Escherichia coli (Nature, 1972)
- Change in methylation of 16S ribosomal RNA associated with mutation to kasugamycin resistance in Escherichia coli. (Nature, 1971)
- Inhibition by kasugamycin of initiation complex formation on 30S ribosomes (Biochemical and Biophysical Research Communications, 1971)
- Improvement of kasugamycin-producing strain by the agar piece method and the prototroph method (Folia Microbiologica, 1971)
- An Unexpected Type of Ribosomes Induced by Kasugamycin: A Look into Ancestral Times of Protein Synthesis? (Molecular Cell, 2009)
- The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation (Nature Structural & Molecular Biology, 2006)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - kasugamycin, phosphate salt
- kasugamycin monohydrochloride
- 3-O-(2-amino-4((carboxyiminomethyl)amino)-2,3,4,6-tetradeoxy-alpha-D-arabino-hexopyranosyl)-D-chiroinositol
- kasugamycin hydrochloride
- kasugamycin, sulfate salt
-
SMILESCC1C(CC(C(O1)OC2C(C(C(C(C2O)O)O)O)O)N)N=C(C(=O)O)N
-
InChIKeyPVTHJAPFENJVNC-UHFFFAOYSA-N
- Pubchem - KASUGAMYCIN
- Wikipedia - kasugamycin
Kasugamycin (Ksg) is an aminoglycoside antibiotic that was originally isolated in 1965, from Streptomyces kasugaensis, a Streptomyces strain found near the Kasuga shrine in Nara, Japan. Kasugamycin was discovered by Hamao Umezawa, who also discovered kanamycin and bleomycin, as a drug which could prevent growth of a fungus causing rice blast disease. It was later found to inhibit bacterial growth also.
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