| Weight | 242.231 g/mol |
|---|---|
| Formula | C10H14N2O5 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 2 |
Telbivudine (3424-98-4)
Score:
#14 in Virology
,
#233 in Microbiology
,
#2214 in Biology
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- Telbivudine versus lamivudine in patients with chronic hepatitis B. (The New England Journal of Medicine, 2007)
- 2-Year GLOBE trial results: telbivudine Is superior to lamivudine in patients with chronic hepatitis B. (Gastroenterology, 2009)
- A 1-year trial of telbivudine, lamivudine, and the combination in patients with hepatitis B e antigen-positive chronic hepatitis B. (Gastroenterology, 2005)
- A prospective and open-label study for the efficacy and safety of telbivudine in pregnancy for the prevention of perinatal transmission of hepatitis B virus infection. (Journal of Hepatology, 2011)
- Treatment of Hepatitis B e Antigen-Positive Chronic Hepatitis with Telbivudine or Adefovir: A Randomized Trial (Annals of Internal Medicine, 2007)
- Baseline characteristics and early on-treatment response predict the outcomes of 2 years of telbivudine treatment of chronic hepatitis B. (Journal of Hepatology, 2009)
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Predict GHS Hazards for Any Chemical in silico.
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SMILESCC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)O
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- Pubchem - Telbivudine
- Wikipedia - telbivudine
Telbivudine is an antiviral drug used in the treatment of hepatitis B infection. It is marketed by Swiss pharmaceutical company Novartis under the trade names Sebivo (Europe) and Tyzeka (United States). Clinical trials have shown it to be significantly more effective than lamivudine or adefovir, and less likely to cause resistance.
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