| Weight | 228.298 g/mol |
|---|---|
| Formula | C8H8N2O2S2 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 1 |
Thiolutin (87-11-6)
"What do you need help with?"
LabBot
- The structures of thiolutin and aureothricin, antibiotics containing a unique pyrrolinonodithiole nucleus (Journal of the American Chemical Society, 1955)
- Mode of action of thiolutin, an inhibitor of macromolecular synthesis in Saccharomyces cerevisiae. (Antimicrobial Agents and Chemotherapy, 1973)
- Inhibition of Yeast Ribonucleic Acid Polymerases by Thiolutin (Journal of Bacteriology, 1973)
- Thiolutin, an inhibitor of HUVEC adhesion to vitronectin, reduces paxillin in HUVECs and suppresses tumor cell-induced angiogenesis (International Journal of Cancer, 2001)
- The transcriptional inhibitor thiolutin blocks mRNA degradation in yeast. (Yeast, 2008)
- Isolation ofiso-butyropyrrothine along with thiolutin and aureothricin from aStreptomyces sp. (Cellular and Molecular Life Sciences, 1960)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(=O)NC1=C2C(=CSS2)N(C1=O)C
-
InChIKeyMHMRAFONCSQAIA-UHFFFAOYSA-N
- Pubchem - Thiolutin
- Wikipedia - thiolutin
Thiolutin is a sulfur-containing antibiotic, which is a potent inhibitor of bacterial and yeast RNA polymerases. It was found to inhibit in vitro RNA synthesis directed by all three yeast RNA polymerases (I, II, and III). Thiolutin is also an inhibitor of mannan and glucan formation in Saccharomyces cerevisiae and used for the analysis of mRNA stability.
Suppliers
Most-cited Publications
Areas of Application
Safety
Alternate Names
External Links
Similar Compounds
Aureothricin
(574-95-8)
1 alternate name
3 suppliers
thiostrepton
(1393-48-2)
1 alternate name
3 suppliers
Leurosidine sulfate
(18556-44-0)
1 alternate name
3 suppliers
Chetomin
(1403-36-7)
1 alternate name
3 suppliers
IRINOTECAN HYDROCHLORIDE Trihydrate
(136572-09-3)
1 alternate name
3 suppliers
Bleomycin sulfate
(11056-06-7, 9041-93-4)
1 alternate name
3 suppliers
Rubitecan
(91421-42-0)
1 alternate name
3 suppliers
Cyanocobalamine
(68-19-9)
1 alternate name
3 suppliers
vitamin B12
(13408-78-1, 68-19-9)
1 alternate name
3 suppliers
Cyanokit
(13422-51-0)
1 alternate name
3 suppliers
TOPOTECAN HYDROCHLORIDE
(119413-54-6)
1 alternate name
3 suppliers
vineomycin a1
(78164-00-8)
1 alternate name
3 suppliers
126643-37-6
(126643-37-6)
1 alternate name
3 suppliers
penitrem A
(12627-35-9)
1 alternate name
3 suppliers
Nadph tetrasodium salt
(2646-71-1)
1 alternate name
3 suppliers
7-amino-AMD
(7240-37-1)
1 alternate name
3 suppliers
69898-40-4
(69898-40-4)
1 alternate name
3 suppliers
NADH (disodium salt)
(606-68-8)
1 alternate name
3 suppliers
Puromycin hydrochloride
(58-58-2)
1 alternate name
3 suppliers
ATORVASTATIN CALCIUM
(110862-48-1, 134523-03-8)
1 alternate name
3 suppliers
Rifamycin S
(13553-79-2)
1 alternate name
3 suppliers
AC1L4AIM
(73069-23-5)
1 alternate name
3 suppliers
Doxorubicin Hydrochloride
(25316-40-9)
1 alternate name
3 suppliers
UNII-U3L0HCE5OI
(6885-57-0)
1 alternate name
3 suppliers
Brucine hydrochloride
(5786-96-9)
1 alternate name
3 suppliers
Tezosentan
(180384-57-0)
1 alternate name
3 suppliers
Lestaurtinib
(111358-88-4)
1 alternate name
3 suppliers
sulforhodamine 101
(60311-02-6)
1 alternate name
3 suppliers
NADP (sodium salt)
(1184-16-3)
1 alternate name
3 suppliers
UNII-1ZCR3Z51KV
(24292-60-2)
1 alternate name
3 suppliers
CEFOPERAZONE SODIUM
(62893-20-3)
1 alternate name
3 suppliers
CEFOTAXIME SODIUM
(64485-93-4)
1 alternate name
3 suppliers
Coenzyme A, trilithium salt
(18439-24-2)
1 alternate name
3 suppliers
96323-20-5
(96323-20-5)
1 alternate name
3 suppliers
Olmesartan medoxomil
(144689-63-4)
1 alternate name
3 suppliers
BETA-AMANITIN
(21150-22-1)
1 alternate name
3 suppliers
3-acetylpyridine adenine dinucleotide
(86-08-8)
1 alternate name
3 suppliers
Salvianolic acid B
(121521-90-2)
1 alternate name
3 suppliers
Aflatoxin Ro
(30419-23-9, 29611-03-8)
1 alternate name
3 suppliers
AFLATOXIN G1
(1165-39-5)
1 alternate name
3 suppliers
3493-13-8
(3493-13-8)
1 alternate name
3 suppliers
24346-00-7
(24346-00-7)
1 alternate name
3 suppliers
AFLATOXIN G2
(7241-98-7)
1 alternate name
3 suppliers
Reactive Orange 14
(12225-86-4)
1 alternate name
3 suppliers
Rutaecarpine
(84-26-4)
1 alternate name
3 suppliers
Oxacillin sodium hydrate
(1173-88-2, 7240-38-2)
1 alternate name
3 suppliers
152881-18-0
(152881-18-0)
1 alternate name
3 suppliers
Arbidol
(131707-25-0)
1 alternate name
3 suppliers
Candesartan cilexetil
(145040-37-5)
1 alternate name
3 suppliers
Fumitremorgin C
(118974-02-0)
1 alternate name
3 suppliers
10-Deacetyltaxol
(78432-77-6, 111149-94-1)
1 alternate name
3 suppliers
Vineomycin B2
(80928-52-5)
1 alternate name
3 suppliers
4-ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione
(10298-40-5)
1 alternate name
3 suppliers
40277-49-4
(40277-49-4)
1 alternate name
3 suppliers
11J-560S
(62522-87-6)
1 alternate name
3 suppliers
Aflatoxin B1
(1162-65-8)
1 alternate name
3 suppliers
902-04-5
(902-04-5)
1 alternate name
3 suppliers
AFLATOXIN B2
(7220-81-7)
1 alternate name
3 suppliers
3-(6,6-dimethyl-3-oxotetrahydro-2H-pyran-2-yl)-3-hydroxy-1,3-dihydro-2H-indol-2-one
(361179-31-9)
1 alternate name
3 suppliers
121626-22-0
(121626-22-0)
1 alternate name
3 suppliers
Manidipine dihydrochloride
(89226-75-5)
1 alternate name
3 suppliers
Uridine 2',3',5'-tribenzoate
(1748-04-5)
1 alternate name
3 suppliers
Fendosal
(53597-27-6)
1 alternate name
3 suppliers
Calcium levofolinate
(80433-71-2, 1492-18-8)
1 alternate name
3 suppliers
Enterocin
(59678-46-5)
1 alternate name
3 suppliers
31188-91-7
(31188-91-7)
1 alternate name
3 suppliers
AMLODIPINE BESYLATE
(111470-99-6)
1 alternate name
3 suppliers
Chlorfenapyr
(122453-73-0)
1 alternate name
5 safety hazards
3 suppliers
Ulifloxacin
(112984-60-8)
1 alternate name
3 suppliers
1-(3-chlorophenyl)-3-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)urea
(325850-26-8)
1 alternate name
3 suppliers
15811-32-2
(15811-32-2)
1 alternate name
3 suppliers
Incazane
(53734-79-5)
1 alternate name
3 suppliers
IMAZETHAPYR
(81335-77-5)
1 alternate name
3 suppliers
429658-95-7
(429658-95-7)
1 alternate name
3 suppliers
371206-03-0
(371206-03-0)
1 alternate name
3 suppliers
Thiolutin
CAS Directory
