| Weight | 278.304 g/mol |
|---|---|
| Formula | C6H14O8S2 |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 7 |
Treosulfan
treosulfan, (R-(R*,R*))-isomer · treosulfan, (R*,S*)-isomer · L-dihydroxybusulfan
299-75-2, 13308-13-9, 1947-62-2
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- Treosulfan and fludarabine: a new toxicity-reduced conditioning regimen for allogeneic hematopoietic stem cell transplantation (Blood, 2004)
- Allogeneic hematopoietic stem cell transplantation in thalassemia major: results of a reduced-toxicity conditioning regimen based on the use of treosulfan (Blood, 2012)
- Clinical Phase I Dose Escalation and Pharmacokinetic Study of High-Dose Chemotherapy with Treosulfan and Autologous Peripheral Blood Stem Cell Transplantation in Patients with Advanced Malignancies (Clinical Cancer Research, 2000)
- Treosulfan-based conditioning regimens for hematopoietic stem cell transplantation in children with primary immunodeficiency: United Kingdom experience (Blood, 2011)
- Acute non-lymphocytic leukemia in patients with ovarian carcinoma following long-term treatment with treosulfan (=dihydroxybusulfan) (Cancer, 1980)
- DNA alkylation and interstrand cross-linking by treosulfan. (British Journal of Cancer, 1999)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - treosulfan, (R-(R*,R*))-isomer
- treosulfan, (R*,S*)-isomer
- L-dihydroxybusulfan
- L-threitol-1,4-bismethanesulfonate
- NSC 39069
- treosulfan, (R*,R*)-isomer
- treosulfan, ((R*,R*)-(+-))-isomer
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SMILESCS(=O)(=O)OCC(C(COS(=O)(=O)C)O)O
-
InChIKeyYCPOZVAOBBQLRI-UHFFFAOYSA-N
- Pubchem - Treosulfan
- Wikipedia - treosulfan
Treosulfan is a substance that is being studied in the treatment of cancer. It belongs to the family of drugs called alkylating agents. It has been used mainly as a substitute of busulfan in frail patients, as the side effects and toxicity are supposedly less severe.
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