| Weight | 314.366 g/mol |
|---|---|
| Formula | C16H14N2O3S |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 3 |
Valdecoxib (181695-72-7)
Score:
#8 in Medicinal chemistry
,
#1731 in Biology
,
#2042 in Chemistry
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- Complications of the COX-2 Inhibitors Parecoxib and Valdecoxib after Cardiac Surgery (The New England Journal of Medicine, 2005)
- 4-[5-Methyl-3-phenylisoxazol-4-yl]- benzenesulfonamide, Valdecoxib: A Potent and Selective Inhibitor of COX-2 (Journal of Medicinal Chemistry, 2000)
- Efficacy and safety of the cyclooxygenase 2 inhibitors parecoxib and valdecoxib in patients undergoing coronary artery bypass surgery (The Journal of Thoracic and Cardiovascular Surgery, 2003)
- Cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs (etodolac, meloxicam, celecoxib, rofecoxib, etoricoxib, valdecoxib and lumiracoxib) for osteoarthritis and rheumatoid arthritis: a systematic review and economic evaluation. (Health Technology Assessment, 2008)
- Safety and efficacy of the cyclooxygenase-2 inhibitors parecoxib and valdecoxib after noncardiac surgery. (Anesthesiology, 2006)
- Valdecoxib, a COX-2-specific inhibitor, is an efficacious, opioid-sparing analgesic in patients undergoing hip arthroplasty (American Journal of Therapeutics, 2002)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1=C(C(=NO1)C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)N
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InChIKeyLNPDTQAFDNKSHK-UHFFFAOYSA-N
- Pubchem - Valdecoxib
- Wikipedia - valdecoxib
Valdecoxib is a nonsteroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms. It is a selective cyclooxygenase-2 inhibitor. Valdecoxib was manufactured and marketed under the brand name Bextra by G.
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CHLOROBENZENE
(Decarboxylative coupling)
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Valdecoxib
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