Weight | 923.051 g/mol |
---|---|
Formula | C46H58N4O14S |
Hydrogen Acceptors | 14 |
Hydrogen Donors | 5 |
Aromatic Rings | 3 |
Rotatable Bonds | 8 |
Vincristine sulfate (2068-78-2)
Vincristine · Oncovin · Leurocristine
Score:
#692 in Neuroscience
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#1247 in Biochemistry
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#3089 in Biology
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#3860 in Chemistry
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- Overcoming of Vincristine Resistance in P388 Leukemia in Vivo and in Vitro through Enhanced Cytotoxicity of Vincristine and Vinblastine by Verapamil (Cancer Research, 1981)
- Frontline therapy with rituximab added to the combination of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) significantly improves the outcome for patients with advanced-stage follicular lymphoma compared with therapy with CHOP alone: results of a prospective randomized study of the German Low-Grade Lymphoma Study Group (Blood, 2005)
- Topotecan versus cyclophosphamide, doxorubicin, and vincristine for the treatment of recurrent small-cell lung cancer. (Journal of Clinical Oncology, 1999)
- Adjuvant procarbazine, lomustine, and vincristine improves progression-free survival but not overall survival in newly diagnosed anaplastic oligodendrogliomas and oligoastrocytomas: a randomized European Organisation for Research and Treatment of Cancer phase III trial. (Journal of Clinical Oncology, 2006)
- Increased Accumulation of Vincristine and Adriamycin in Drug-resistant P388 Tumor Cells following Incubation with Calcium Antagonists and Calmodulin Inhibitors (Cancer Research, 1982)
- NOA-04 Randomized Phase III Trial of Sequential Radiochemotherapy of Anaplastic Glioma With Procarbazine, Lomustine, and Vincristine or Temozolomide (Journal of Clinical Oncology, 2009)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Vincristine
- Oncovin
- Leurocristine
- Vincasar
- Vincasar PFS
- cellcristin
- Vincristin medac
- Vincrisul
- Vintec
- Onkocristin
- Vincristin Bristol
- Oncovine
- Farmistin
- Citomid
-
SMILESCCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O
-
InChIKeyAQTQHPDCURKLKT-UHFFFAOYSA-N
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