| Weight | 224.259 g/mol |
|---|---|
| Formula | C15H12O2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 3 |
2-Hydroxychalcone (644-78-0)
Score:
#96 in Physical chemistry
,
#2247 in Physics
,
#6955 in Chemistry
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- Chemoprevention of 4-Nitroquinoline 1-Oxide-induced Rat Oral Carcinogenesis by the Dietary Flavonoids Chalcone, 2-Hydroxychalcone, and Quercetin (Cancer Research, 1996)
- Inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase and tumor necrosis factor- by 2'-hydroxychalcone derivatives in RAW 264.7 cells (Biochemical Pharmacology, 2004)
- The chemistry of 2'-amino analogs of 2'-hydroxychalcone and its derivatives (Journal of Organic Chemistry, 1990)
- 2-Hydroxychalcone Inhibits Nuclear Factor-B and Blocks Tumor Necrosis Factor-- and Lipopolysaccharide-Induced Adhesion of Neutrophils to Human Umbilical Vein Endothelial Cells (Molecular Pharmacology, 2000)
- Efficient NIR-Light Emission from Solid-State Complexes of Boron Difluoride with 2-Hydroxychalcone Derivatives (Chemistry: A European Journal, 2012)
- Heme oxygenase-1 mediates the anti-inflammatory actions of 2-hydroxychalcone in RAW 264.7 murine macrophages (American Journal of Physiology-cell Physiology, 2006)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1=CC=C(C=C1)C(=O)C=CC2=CC=CC=C2O
-
InChIKeyUDOOPSJCRMKSGL-UHFFFAOYSA-N
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Synthesis
Reactant
+
2-CHLOROPHENOL
(Stille)
benzene
+
Reactant
(Friedel-Crafts acylation)
Reactant
+
CHLOROBENZENE
(Grignard carbonyl)
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2-Hydroxychalcone
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