| Weight | 130.195 g/mol |
|---|---|
| Formula | C5H14N4 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 4 |
agmatine (306-60-5)
1-Amino-4-guanidinobutane · 4-(Aminobutyl)guanidine · 1 Amino 4 guanidinobutane
Score:
#560 in Neuroscience
,
#955 in Biochemistry
,
#2527 in Biology
,
#3149 in Chemistry
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- Agmatine: An endogenous clonidine-displacing substance in the brain (Science, 1994)
- Is agmatine a novel neurotransmitter in brain (Trends in Pharmacological Sciences, 2000)
- Inhibition of mammalian nitric oxide synthases by agmatine, an endogenous polyamine formed by decarboxylation of arginine (Biochemical Journal, 1996)
- Agmatine, the bacterial amine, is widely distributed in mammalian tissues (Life Sciences, 1995)
- Agmatine Selectively Blocks theN-Methyl-d-Aspartate Subclass of Glutamate Receptor Channels in Rat Hippocampal Neurons (Journal of Pharmacology and Experimental Therapeutics, 1999)
- Agmatine reverses pain induced by inflammation, neuropathy, and spinal cord injury (Proceedings of the National Academy of Sciences of the United States of America, 2000)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 1-Amino-4-guanidinobutane
- 4-(Aminobutyl)guanidine
- 1 Amino 4 guanidinobutane
-
SMILESC(CCN=C(N)N)CN
-
InChIKeyQYPPJABKJHAVHS-UHFFFAOYSA-N
- Pubchem - agmatine
- Wikipedia - agmatine
Agmatine, also known as (4-aminobutyl)guanidine, is an aminoguanidine that was discovered in 1910 by Albrecht Kossel. Agmatine is a chemical substance which is naturally created from the chemical arginine. Agmatine has been shown to exert modulatory action at multiple molecular targets, notably: neurotransmitter systems, ion channels, nitric oxide (NO) synthesis and polyamine metabolism and this provides bases for further research into potential applications.
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