| Weight | 327.424 g/mol | 
|---|---|
| Formula | C20H25NO3 | 
| Hydrogen Acceptors | 4 | 
| Hydrogen Donors | 1 | 
| Aromatic Rings | 2 | 
| Rotatable Bonds | 8 | 
BENACTYZINE (302-40-9)
Amizil · Amizyl · Lucidil
 Score:
          #538 in Neuroscience
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          #2457 in Biology
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          #3061 in Chemistry
          
        
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 - The action of atropine benactyzine, and scopolamine upon fixed-interval and fixed-ratio behavior (Journal of the Experimental Analysis of Behavior, 1959)
 - The Effect of Benzilic Acid Diethylaminoethylester, HCl (Benactyzine) on Stress-Induced Behaviour in the Rat.* (Pharmacology & Toxicology, 2009)
 - Therapeutic effects of HS-3, HS-6, benactyzine, and atropine in soman poisoning of dogs (Archives of Toxicology, 1976)
 - Therapeutic effects of new oximes, benactyzine and atropine in Soman poisoning: Part I. Effects of various oximes in Soman, Sarin, and Vx poisoning in dogs. (Toxicological Sciences, 1981)
 - EFFECTS OF BENACTYZINE AND ADIPHENINE ON INSTRUMENTAL AVOIDANCE CONDITIONING IN A SHUTTLE-BOX. (Psychopharmacology, 1964)
 - Action of a Series of BenactyzineDerivatives*) and Other Compounds on StressInduced Behaviour in the Rat. (Pharmacology & Toxicology, 2009)
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            Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Amizil
 - Amizyl
 - Lucidil
 - 
          SMILESCCN(CC)CCOC(=O)C(C1=CC=CC=C1)(C2=CC=CC=C2)O
 - 
          InChIKeyIVQOFBKHQCTVQV-UHFFFAOYSA-N
 - Pubchem - BENACTYZINE
 - Wikipedia - benactyzine
          
          Benactyzine is an anticholinergic drug that was used as an antidepressant in the treatment of depression and associated anxiety before it was pulled from the U.S. market by the FDA due to its ineffectiveness. Its use for these indications was limited by side effects such as dry mouth and nausea, and at high doses it can cause more severe symptoms such as deliriant and hallucinogenic effects.
 
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Synthesis
                
                benzene 
                
                
                 + 
                
                Reactant
                
                (Friedel-Crafts alkylation)
                
              
              
        
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