Weight | 310.4 g/mol |
---|---|
Formula | C22H18N2 |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 0 |
Aromatic Rings | 4 |
Rotatable Bonds | 4 |
bifonazole (60628-96-8)
Bifon · Mycospor · Bay H 4502
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- Sigma-Aldrich - bifonazole39.90 - 168.00 USD
- Fisher Scientific - Search for bifonazole
- TCI - bifonazole80.00 - 280.00 USD
- Structure of Microsomal Cytochrome P450 2B4 Complexed with the Antifungal Drug Bifonazole INSIGHT INTO P450 CONFORMATIONAL PLASTICITY AND MEMBRANE INTERACTION (Journal of Biological Chemistry, 2006)
- Clotrimazole and bifonazole detach hexokinase from mitochondria of melanoma cells. (European Journal of Pharmacology, 1998)
- Bifonazole. A review of its antimicrobial activity and therapeutic use in superficial mycoses. (Drugs, 1986)
- Antifungal relative inhibition factors: BAY 19139, bifonazole, butoconazole, isoconazole, itraconazole (R 51211), oxiconazole, Ro 144767/002, sulconazole, terconazole and vibunazole (BAY n-7133) compared in vitro with nine established antifungal agents (Journal of Antimicrobial Chemotherapy, 1984)
- Antimycotic efficacy of bifonazole in vitro and in vivo. (Drug Research, 1983)
- Onychomycosis in children : Treatment with bifonazole-urea (Pediatric Dermatology, 2000)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Bifon
- Mycospor
- Bay H 4502
- Moldina
- Bifomyk
- Bifokey
- Bay H-4502
- Amycor
- Canesten brand of bifonazole
-
SMILESC1=CC=C(C=C1)C2=CC=C(C=C2)C(C3=CC=CC=C3)N4C=CN=C4
-
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- Pubchem - bifonazole
- Wikipedia - bifonazole
Bifonazole (trade name Canespor among many others) is an imidazole antifungal drug used in form of ointments. There are also combinations with carbamide for the treatment of onychomycosis.
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Synthesis
Reactant
+
CHLOROBENZENE
(Stille)
benzoic acid
+
Reactant
(Decarboxylative coupling)
Phenylboronic acid
+
Reactant
(Suzuki)
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