| Weight | 300.336 g/mol |
|---|---|
| Formula | C12H16N2O5S |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 6 |
Carboxytolbutamide (2224-10-4)
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- KINETICS OF CARBOXYTOBUTAMIDE EXCRETION FOLLOWING TOLBUTAMIDE AND CARBOXYTOLBUTAMIDE ADMINISTRATION (Journal of Pharmacology and Experimental Therapeutics, 1961)
- High-performance liquid chromatographic assay of tolbutamide and carboxytolbutamide in human plasma (Journal of Pharmaceutical Sciences, 1981)
- Determination of carboxytolbutamide in urine. (Clinica Chimica Acta, 1960)
- Carboxytolbutamide excretion following subcutaneous implantation of tolbutamide spheres in rats. (Archives internationales de pharmacodynamie et de thrapie, 1961)
- [Extrapancreatic effects of sulfonylurea compounds. II. Comparison of equimolar concentrations of tolbutamide, glibornuride, hydroxymethyltolbutamide, carboxytolbutamide, and carboxyglycylamide with reference to their blood-sugar-decreasing and antilipolytic effect on completely pancreatectomized dogs, chronically treated insulin]. (Drug Research, 1972)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)C(=O)O
-
InChIKeyGCMVATDSSHTCOS-UHFFFAOYSA-N
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Alternate Names
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Synthesis
Reactant
+
Butylamine
(Schotten-Baumann amide from acid)
n-Butylboronic acid
+
Reactant
(Chan-Lam coupling reaction)
Reactant
+
1-Chlorobutane
(Alkylation of primary amines)
Reactant
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
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Carboxytolbutamide
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