| Weight | 319.88 g/mol |
|---|---|
| Formula | C18H26ClN3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 8 |
chloroquine (58175-86-3, 54-05-7)
Aralen · Nivaquine · Chloroquine Sulfate
Score:
#34 in Microbiology
,
#127 in Biochemistry
,
#565 in Biology
,
#601 in Chemistry
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- Mutations in the P. falciparum Digestive Vacuole Transmembrane Protein PfCRT and Evidence for Their Role in Chloroquine Resistance (Molecular Cell, 2000)
- A MOLECULAR MARKER FOR CHLOROQUINE-RESISTANT FALCIPARUM MALARIA (The New England Journal of Medicine, 2001)
- Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum (Nature, 2002)
- Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling. (Journal of Cell Biology, 1980)
- Chloroquine Resistance in Plasmodium falciparum Malaria Parasites Conferred by pfcrt Mutations (Science, 2002)
- PROTEIN DEGRADATION IN CULTURED CELLS: II. The Uptake of Chloroquine by Rat Fibroblasts and the Inhibition of Cellular Protein Degradation and Cathepsin B1 (Journal of Cell Biology, 1974)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Aralen
- Nivaquine
- Chloroquine Sulfate
- Chloroquine Sulphate
- Arequin
- Arechine
- Khingamin
- Chlorochin
- Chingamin
-
SMILESCCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl
-
InChIKeyWHTVZRBIWZFKQO-UHFFFAOYSA-N
- Pubchem - chloroquine
- Wikipedia - chloroquine
Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. It is also occasionally used for amebiasis that is occurring outside the intestines, rheumatoid arthritis, and lupus erythematosus.
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