| Weight | 320.324 g/mol |
|---|---|
| Formula | C19H14NO4+ |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 0 |
Coptisine (3486-66-6)
Score:
#632 in Biochemistry
,
#1807 in Biology
,
#2153 in Chemistry
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- Sigma-Aldrich - Search for Coptisine
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- Cytotoxic effects of Coptis chinensis and Epimedium sagittatum extracts and their major constituents (berberine, coptisine and icariin) on hepatoma and leukaemia cell growth (Clinical and Experimental Pharmacology and Physiology, 2004)
- Analysis of coptisine, berberine and palmatine in adulterated Chinese medicine by capillary electrophoresis-electrospray ion trap mass spectrometry. (Journal of Chromatography A, 2000)
- A sensitive and specific liquid chromatography mass spectrometry method for simultaneous determination of berberine, palmatine, coptisine, epiberberine and jatrorrhizine from Coptidis Rhizoma in rat plasma (International Journal of Mass Spectrometry, 2007)
- Antispasmodic and relaxant activity of chelidonine, protopine, coptisine, and Chelidonium majus extracts on isolated guinea-pig ileum (Planta Medica, 1998)
- Determination of coptisine, berberine and palmatine in traditional Chinese medicinal preparations by capillary electrophoresis (Journal of Chromatography A, 1993)
- Simultaneous Determination of Berberine, Palmatine and Coptisine in Crude Drugs and Oriental Pharmaceutical Preparations by Ion-Pair High-Performance Liquid Chromatography (Chemical & Pharmaceutical Bulletin, 1982)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1C[N+]2=C(C=C3C=CC4=C(C3=C2)OCO4)C5=CC6=C(C=C51)OCO6
-
InChIKeyXYHOBCMEDLZUMP-UHFFFAOYSA-N
- Pubchem - Coptisine
- Wikipedia - coptisine
Coptisine is an alkaloid found in Chinese goldthread (Coptis chinensis). Famous for the bitter taste that it produces, it is used in Chinese herbal medicine along with the related compound berberine for treating digestive disorders caused by bacterial infections. Also found in Greater Celandine and has also been detected in Opium.
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