| Weight | 345.208 g/mol |
|---|---|
| Formula | C10H12N5O7P |
| Hydrogen Acceptors | 10 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 1 |
cyclic gmp (7665-99-8)
Guanosine Cyclic Monophosphate · Guanosine Cyclic-3',5'-Monophosphate · Guanosine Cyclic 3',5'-Monophosphate
Score:
#1177 in Biochemistry
,
#2977 in Biology
,
#3720 in Chemistry
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- Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. (Journal of Clinical Investigation, 1989)
- Nitric oxide activates guanylate cyclase and increases guanosine 3:5-cyclic monophosphate levels in various tissue preparations (Proceedings of the National Academy of Sciences of the United States of America, 1977)
- Defense gene induction in tobacco by nitric oxide, cyclic GMP, and cyclic ADP-ribose (Proceedings of the National Academy of Sciences of the United States of America, 1998)
- Guanylyl Cyclases and Signaling by Cyclic GMP (Pharmacological Reviews, 2000)
- Induction by cyclic GMP of cationic conductance in plasma membrane of retinal rod outer segment (Nature, 1985)
- Sildenafil: an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction. (International Journal of Impotence Research, 1996)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Guanosine Cyclic Monophosphate
- Guanosine Cyclic-3',5'-Monophosphate
- Guanosine Cyclic 3',5'-Monophosphate
- Guanosine Cyclic 3,5 Monophosphate
- Guanosine Cyclic 3',5' Monophosphate
-
SMILESC1C2C(C(C(O2)N3C=NC4=C3NC(=NC4=O)N)O)OP(=O)(O1)O
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InChIKeyZOOGRGPOEVQQDX-UHFFFAOYSA-N
- Pubchem - cyclic gmp
- Wikipedia - guanosine cyclic 3',5'-phosphate
Cyclic guanosine monophosphate (cGMP) is a cyclic nucleotide derived from guanosine triphosphate (GTP). cGMP acts as a second messenger much like cyclic AMP. Its most likely mechanism of action is activation of intracellular protein kinases in response to the binding of membrane-impermeable peptide hormones to the external cell surface.
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