| Weight | 416.945 g/mol |
|---|---|
| Formula | C24H29ClO4 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 2 |
CYPROTERONE ACETATE (427-51-0)
Androcur · Cyproterone Acetate, (17 alpha)-Isomer · Cyproterone Acetate, (1 alpha,2 alpha,9 beta,10 alpha)-Isomer
Score:
#425 in Biochemistry
,
#1425 in Biology
,
#1667 in Chemistry
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- Endocrine and metabolic effects of metformin versus ethinyl estradiol-cyproterone acetate in obese women with polycystic ovary syndrome: a randomized study. (The Journal of Clinical Endocrinology and Metabolism, 2000)
- Use of cyproterone acetate (CPA) in the treatment of acne, hirsutism and virilism (Journal of Steroid Biochemistry, 1975)
- Altered cognitive function in men treated for prostate cancer with luteinizing hormone-releasing hormone analogues and cyproterone acetate: A randomized controlled trial (BJUI, 2002)
- A double-blind controlled cross-over trial of cyproterone acetate in females with hidradenitis suppurativa (British Journal of Dermatology, 1986)
- Comparison of diethylstilbestrol, cyproterone acetate and medroxyprogesterone acetate in the treatment of advanced prostatic cancer: final analysis of a randomized phase III trial of the European Organization for Research on Treatment of Cancer Urological Group. (The Journal of Urology, 1986)
- Cardiovascular Side Effects of Diethylstilbestrol, Cyproterone Acetate, Medroxyprogesterone Acetate and Estramustine Phosphate Used for the Treatment of Advanced Prostatic Cancer: Results from European Organization for Research on Treatment of Cancer Trials 30761 and 30762 (The Journal of Urology, 1986)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Androcur
- Cyproterone Acetate, (17 alpha)-Isomer
- Cyproterone Acetate, (1 alpha,2 alpha,9 beta,10 alpha)-Isomer
- Cyproterone Acetate, (1 alpha,2 alpha)-Isomer
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SMILESCC(=O)C1(CCC2C1(CCC3C2C=C(C4=CC(=O)C5CC5C34C)Cl)C)OC(=O)C
-
InChIKeyUWFYSQMTEOIJJG-UHFFFAOYSA-N
- Pubchem - CYPROTERONE ACETATE
- Wikipedia - cyproterone acetate
Cyproterone acetate (abbreviated as CPA), sold alone under the brand name Androcur or with ethinylestradiol (EE) under the brand names Diane or Diane-35 among others, is an antiandrogen and progestogen which is used in the treatment of androgen-dependent conditions like acne, excessive hair growth, early puberty, and prostate cancer, as a component of feminizing hormone therapy for transgender women, and in birth control pills. It is formulated and used both alone and in combination with an estrogen and is available for use both by mouth and by injection into muscle. Common side effects of non-contraceptive (i.e., high) dosages of CPA in men include gynecomastia (breast development) and feminization in general and in both men and women include hypogonadism (low sex hormone levels), reversible infertility, sexual dysfunction, mental symptoms like depression, fatigue, and irritability, vitamin B12 deficiency, and elevated liver enzymes.
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CYPROTERONE ACETATE
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