| Weight | 776.872 g/mol |
|---|---|
| Formula | C15H11I4NO4 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 5 |
D-Thyroxine (137-53-1, 51-49-0)
Dextrothyroxine · Choloxin · Dextrothyroxine Sodium
Score:
#1019 in Biochemistry
,
#2664 in Biology
,
#3329 in Chemistry
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- Sigma-Aldrich - D-Thyroxine128.75 USD
- Fisher Scientific - Search for D-Thyroxine
- TCI - Search for D-Thyroxine
- The Coronary Drug Project: Findings Leading to Further Modifications of Its Protocol With Respect to Dextrothyroxine (JAMA, 1972)
- II. The effect of D-thyroxine, clofibrate, and norethandrolone (Clinical Pharmacology & Therapeutics, 1967)
- D-propranolol and DL-propranolol both decrease conversion of L-thyroxine to L-triiodothyronine. (BMJ, 1980)
- Effect of Sodium Dextrothyroxine in Patients Receiving Anticoagulants (The New England Journal of Medicine, 1962)
- L-Thyroxine contamination of pharmaceutical D-thyroxine: Probable cause of therapeutic effect (Clinical Pharmacology & Therapeutics, 1984)
- Thyroxine signal transduction in liver cells involves phospholipase C and phospholipase D activation. Genomic independent action of thyroid hormone (BMC Cell Biology, 2001)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Dextrothyroxine
- Choloxin
- Dextrothyroxine Sodium
- Sodium Dextrothyroxine
- D Thyroxine
- D-T4 Thyroid Hormone
-
SMILESC1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)CC(C(=O)O)N
-
InChIKeyXUIIKFGFIJCVMT-UHFFFAOYSA-N
- Pubchem - D-Thyroxine
- Wikipedia - dextrothyroxine
Dextrothyroxine (trade name Choloxin) saw research as a cholesterol-lowering drug but was pulled due to cardiac side-effects. It also increases hepatic lipase which in turn improves utilization of triglycerides, improving apolipoprotein E cholesterol particles.
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