Weight | 560.693 g/mol |
---|---|
Formula | C25H48N6O8 |
Hydrogen Acceptors | 9 |
Hydrogen Donors | 6 |
Aromatic Rings | 0 |
Rotatable Bonds | 23 |
deferoxamine (70-51-9, 1950-39-6)
Desferrioxamine · Desferal · Deferoxamine Mesylate
Score:
#2031 in Biology
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#2483 in Chemistry
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- Survival and complications in patients with thalassemia major treated with transfusion and deferoxamine (Haematologica, 2004)
- Efficacy of deferoxamine in preventing complications of iron overload in patients with thalassemia major (The New England Journal of Medicine, 1994)
- Desferrioxamine induces erythropoietin gene expression and hypoxia- inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction (Blood, 1993)
- Inhibition of the iron-catalysed formation of hydroxyl radicals from superoxide and of lipid peroxidation by desferrioxamine. (Biochemical Journal, 1979)
- Intramuscular desferrioxamine in patients with Alzheimer's disease (The Lancet, 1991)
- The Biochemistry of Desferrioxamine and its Relation to Iron Metabolism (Annals of the New York Academy of Sciences, 2006)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Desferrioxamine
- Desferal
- Deferoxamine Mesylate
- Desferrioxamine B
- Desferioximine
- Deferoximine
- Deferoxamine Methanesulfonate
- Deferoxamine Mesilate
- Desferroxamine
- Deferoxamine B
- Deferrioxamine B
- Desferrioxamine B Mesylate
-
SMILESCC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCN)O)O)O
-
InChIKeyUBQYURCVBFRUQT-UHFFFAOYSA-N
- Pubchem - deferoxamine
- Wikipedia - deferoxamine
Deferoxamine (DFOA), sold under the brand name Desferal, is a medication that binds iron and aluminium. It is specifically used in iron overdose, hemochromatosis either due to multiple blood transfusions or an underlying genetic condition, and aluminium toxicity in people on dialysis. It is used by injection into a muscle, vein, or under the skin.
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