Weight | 271.404 g/mol |
---|---|
Formula | C18H25NO |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 0 |
Aromatic Rings | 1 |
Rotatable Bonds | 1 |
dextromethorphan
Dextromethorphan Hydrobromide · Delsym · Levomethorphan
510-53-2, 125-71-3, 125-70-2
Score:
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- Polymorphic dextromethorphan metabolism: co-segregation of oxidative O-demethylation with debrisoquin hydroxylation (Clinical Pharmacology & Therapeutics, 1985)
- High-dose oral dextromethorphan versus placebo in painful diabetic neuropathy and postherpetic neuralgia. (Neurology, 1997)
- THE N-METHYL-D-ASPARTATE RECEPTOR ANTAGONIST DEXTROMETHORPHAN SELECTIVELY REDUCES TEMPORAL SUMMATION OF SECOND PAIN IN MAN (Pain, 1994)
- Dextromethorphan decreases the excitability of the human motor cortex (Neurology, 1998)
- High-performance liquid chromatographic assays for bufuralol 1-hydroxylase, debrisoquine 4-hydroxylase, and dextromethorphan O-demethylase in microsomes and purified cytochrome P-450 isozymes of human liver (Analytical Biochemistry, 1987)
- Research reportThe N-methyl-d-aspartate receptor antagonist dextromethorphan selectively reduces temporal summation of second pain in man (Pain, 1994)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Dextromethorphan Hydrobromide
- Delsym
- Levomethorphan
- l-Methorphan
- Dextromethorphan Hydrobromide, Monohydrate
- Dextromethorphan, (+-)-Isomer
- Dextromethorphan Hydrobromide, (+-)-Isomer
- Racemethorphan
- Dextromethorphan Hydrochloride
- d-Methorphan
-
SMILESCN1CCC23CCCCC2C1CC4=C3C=C(C=C4)OC
-
InChIKeyMKXZASYAUGDDCJ-UHFFFAOYSA-N
- Pubchem - dextromethorphan
- Wikipedia - Methorphan
Methorphan comes in two isomeric forms, each with differing pharmacology and effects: Dextromethorphan - An over-the-counter cough suppressant, as well as dissociative hallucinogen. Levomethorphan - A potent opioid analgesic that was never clinically developed; the codeine analogue of the powerful opioid agonist analgesic levorphanol (Levo-Dromoran). Racemethorphan refers to the racemic mixture of both of these stereoisomers.
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