| Weight | 583.596 g/mol |
|---|---|
| Formula | C21H41N7O12 |
| Hydrogen Acceptors | 15 |
| Hydrogen Donors | 13 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 9 |
dihydrostreptomycin (128-46-1)
Dihydrostreptomycin Sulfate · Citrocil
Score:
#505 in Microbiology
,
#1863 in Biochemistry
,
#4014 in Biology
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#5056 in Chemistry
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- The aminoglycoside antibiotic dihydrostreptomycin rapidly enters mouse outer hair cells through the mechano-electrical transducer channels (The Journal of Physiology, 2005)
- Antibiotic Therapy of Bacterial Endocarditis IV. Successful Short-Term (Two Weeks) Combined Penicillin-Dihydrostreptomycin Therapy in Subacute Bacterial Endocarditis Caused by Penicillin-Sensitive Streptococci (Circulation, 1953)
- Chloramphenicol-, Dihydrostreptomycin-, and Kanamycin-Inactivating Enzymes from Multiple Drug-Resistant Escherichia coli Carrying Episome R (Nature, 1965)
- Inhibition of cytochrome systems of heart muscle and certain bacteria by the antagonists of dihydrostreptomycin: 2-alkyl-4-hydroxyquinoline N-oxides. (Biochemical Journal, 1956)
- Structure of a naturally occurring antagonist of dihydrostreptomycin (Biochemical Journal, 1956)
- Binding of Dihydrostreptomycin to Escherichia coli Ribosomes: Characteristics and Equilibrium of the Reaction (Antimicrobial Agents and Chemotherapy, 1972)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Dihydrostreptomycin Sulfate
- Citrocil
-
SMILESCC1C(C(C(O1)OC2C(C(C(C(C2O)O)N=C(N)N)O)N=C(N)N)OC3C(C(C(C(O3)CO)O)O)NC)(CO)O
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InChIKeyASXBYYWOLISCLQ-UHFFFAOYSA-N
- Pubchem - dihydrostreptomycin
- Wikipedia - dihydrostreptomycin
Dihydrostreptomycin is a derivative of streptomycin that has a bactericidal property. It's a semisynthetic aminoglycoside antibiotic used in the treatment of tuberculosis. It acts by irreversibly binding the S12 protein in the bacterial 30S ribosomal subunit, after being actively transported across the cell membrane, which interferes with the initiation complex between the mRNA and the bacterial ribosome.
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