Weight | 213.189 g/mol |
---|---|
Formula | C9H11NO5 |
Hydrogen Acceptors | 5 |
Hydrogen Donors | 5 |
Aromatic Rings | 1 |
Rotatable Bonds | 3 |
droxidopa (3916-18-5, 23651-95-8)
3,4 threo DOPS · 3,4-threo-DOPS · Droxidopa, (DL-Tyr)-Isomer
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- Sigma-Aldrich - droxidopa106.00 - 428.50 USD
- Fisher Scientific - Search for droxidopa
- TCI - droxidopa134.00 - 388.00 USD
- L-threo-dihydroxyphenylserine (L-threo-DOPS; droxidopa) in the management of neurogenic orthostatic hypotension: a multi-national, multi-center, dose-ranging study in multiple system atrophy and pure autonomic failure. (Clinical Autonomic Research, 2001)
- Droxidopa for neurogenic orthostatic hypotension: A randomized, placebo-controlled, phase 3 trial (Neurology, 2014)
- L-dihydroxyphenylserine (Droxidopa) in the treatment of orthostatic hypotension (Clinical Autonomic Research, 2008)
- Randomized withdrawal study of patients with symptomatic neurogenic orthostatic hypotension responsive to droxidopa (Hypertension, 2015)
- L-dihydroxyphenylserine (Droxidopa): a new therapy for neurogenic orthostatic hypotension (Clinical Autonomic Research, 2008)
- Droxidopa for the ShortTerm Treatment of Symptomatic Neurogenic Orthostatic Hypotension in Parkinson's Disease (nOH306B) (Movement Disorders, 2015)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 3,4 threo DOPS
- 3,4-threo-DOPS
- Droxidopa, (DL-Tyr)-Isomer
- erythro 3,4 Dihydroxyphenylserine
- DL-threo-3,4-Dihydroxyphenylserine
- DL threo 3,4 Dihydroxyphenylserine
- 3,4 Dihydroxyphenylserine
- threo-DOPS
- 3,4-Dihydroxyphenylserine
- threo DOPS
- erythro-3,4-Dihydroxyphenylserine
-
SMILESC1=CC(=C(C=C1C(C(C(=O)O)N)O)O)O
-
InChIKeyQXWYKJLNLSIPIN-UHFFFAOYSA-N
- Pubchem - droxidopa
- Wikipedia - droxidopa
Droxidopa (INN; trade name Northera; also known as L-DOPS, L-threo-dihydroxyphenylserine, L-threo-DOPS and SM-5688) is a synthetic amino acid precursor which acts as a prodrug to the neurotransmitter norepinephrine (noradrenaline). Unlike norepinephrine, droxidopa is capable of crossing the protective bloodbrain barrier (BBB).
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