| Weight | 469.669 g/mol |
|---|---|
| Formula | C32H39NO2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 9 |
ebastine (90729-43-4)
Kestin · Bactil · Busidril
Score:
#1538 in Physics
,
#3666 in Biology
,
#4602 in Chemistry
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- Sigma-Aldrich - ebastine187.00 - 780.00 USD
- Fisher Scientific - Search for ebastine
- TCI - ebastine108.00 - 378.00 USD
- Involvement of CYP2J2 and CYP4F12 in the Metabolism of Ebastine in Human Intestinal Microsomes (Journal of Pharmacology and Experimental Therapeutics, 2002)
- A double-blind, randomized, single-dose, crossover comparison of levocetirizine with ebastine, fexofenadine, loratadine, mizolastine, and placebo: suppression of histamine-induced wheal-and-flare response during 24 hours in healthy male subjects. (Annals of Allergy Asthma & Immunology, 2002)
- A double-blind, single-dose, crossover comparison of cetirizine, ebastine, epinastine, fexofenadine, terfenadine, and loratadine versus placebo: suppression of histamine-induced wheal and flare response for 24 h in healthy male subjects (Allergy, 1999)
- Neuroimaging of histamine H1-receptor occupancy in human brain by positron emission tomography (PET): A comparative study of ebastine, a second-generation antihistamine, and (+)-chlorpheniramine, a classical antihistamine (British Journal of Clinical Pharmacology, 2008)
- Ebastine : a review of its pharmacological properties and clinical efficacy in the treatment of allergic disorders (Drugs, 1996)
- Using an innovative Quality-by-Design approach for development of a stability indicating UHPLC method for ebastine in the API and pharmaceutical formulations (Journal of Pharmaceutical and Biomedical Analysis, 2013)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Kestin
- Bactil
- Busidril
- Ebastel
- 4-diphenylmethoxy-1-(3-(4-tert-butylbenzoyl)propyl)piperidine
- LAS W-090
- Kestine
- Evastel
-
SMILESCC(C)(C)C1=CC=C(C=C1)C(=O)CCCN2CCC(CC2)OC(C3=CC=CC=C3)C4=CC=CC=C4
-
InChIKeyMJJALKDDGIKVBE-UHFFFAOYSA-N
- Pubchem - ebastine
- Wikipedia - ebastine
Ebastine (trade names Evastin, Kestine, Ebastel, Aleva, Ebatrol) is a H1 antihistamine with low potential for causing drowsiness. It does not penetrate the bloodbrain barrier to a significant amount and thus combines an effective block of the H1 receptor in peripheral tissue with a low incidence of central side effects, i.e. seldom causing sedation or drowsiness.
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ebastine
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