| Weight | 274.181 g/mol |
|---|---|
| Formula | C13H9NOSe |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 1 |
ebselen (60940-34-3)
2-phenyl-1,2-benzoisoselenazol-3(2H)-one · RP 60931 · DR 3305
Score:
#838 in Neuroscience
,
#1621 in Biochemistry
,
#3686 in Biology
,
#4634 in Chemistry
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- Sigma-Aldrich - ebselen162.50 - 502.00 USD
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- TCI - ebselen57.00 - 170.00 USD
- A novel biologically active seleno-organic compound--I. Glutathione peroxidase-like activity in vitro and antioxidant capacity of PZ 51 (Ebselen). (Biochemical Pharmacology, 1984)
- Ebselen in Acute Ischemic Stroke A Placebo-Controlled, Double-blind Clinical Trial (Stroke, 1998)
- Ebselen, a selenoorganic compound as glutathione peroxidase mimic (Free Radical Biology and Medicine, 1993)
- Molecular actions of Ebselenan antiinflammatory antioxidant (General Pharmacology-the Vascular System, 1995)
- Doxorubicin-induced Apoptosis in Endothelial Cells and Cardiomyocytes Is Ameliorated by Nitrone Spin Traps and Ebselen ROLE OF REACTIVE OXYGEN AND NITROGEN SPECIES (Journal of Biological Chemistry, 2000)
- Ebselen: prospective therapy for cerebral ischaemia (Expert Opinion on Investigational Drugs, 2000)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 2-phenyl-1,2-benzoisoselenazol-3(2H)-one
- RP 60931
- DR 3305
- PZ-51
- PZ 51
- DR-3305
-
SMILESC1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2
-
InChIKeyDYEFUKCXAQOFHX-UHFFFAOYSA-N
- Pubchem - ebselen
- Wikipedia - ebselen
Ebselen (also called PZ 51, DR3305, and SPI-1005), is a synthetic organoselenium drug molecule with anti-inflammatory, anti-oxidant and cytoprotective activity. It acts as a mimic of glutathione peroxidase and can also react with peroxynitrite. It is being investigated as a possible treatment for reperfusion injury and stroke, hearing loss and tinnitus, and bipolar disorder.
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