| Weight | 352.471 g/mol |
|---|---|
| Formula | C20H32O5 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 10 |
epoprostenol
Prostacyclin · PGI2 · Prostaglandin I2
136626-78-3, 61849-14-7, 35121-78-9
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- A Comparison of Continuous Intravenous Epoprostenol (Prostacyclin) with Conventional Therapy for Primary Pulmonary Hypertension (The New England Journal of Medicine, 1996)
- Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin. (Pharmacological Reviews, 1978)
- Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor (Proceedings of the National Academy of Sciences of the United States of America, 1988)
- Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: The human pharmacology of a selective inhibitor of COX-2 (Proceedings of the National Academy of Sciences of the United States of America, 1999)
- Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: Prognostic factors and survival (Journal of the American College of Cardiology, 2002)
- Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension: A double-blind, randomized, placebo-controlled trial (American Journal of Respiratory and Critical Care Medicine, 2002)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Prostacyclin
- PGI2
- Prostaglandin I2
- PGX
- Flolan
- Epoprostenol Sodium
- Epoprostenol Sodium Salt, (5Z,9alpha,11alpha,13E,15S)-Isomer
- Epoprostanol
- Prostaglandin I(2)
-
SMILESCCCCCC(C=CC1C(CC2C1CC(=CCCCC(=O)O)O2)O)O
-
InChIKeyKAQKFAOMNZTLHT-UHFFFAOYSA-N
- Pubchem - epoprostenol
- Wikipedia - Epoprostenol
Prostacyclin (also called prostaglandin I2 or PGI2) is a prostaglandin member of the eicosanoid family of lipid molecules. It inhibits platelet activation and is also an effective vasodilator. When used as a drug, it is also known as epoprostenol.
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