Weight | 360.772 g/mol |
---|---|
Formula | C18H14ClFN2O3 |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 1 |
Aromatic Rings | 2 |
Rotatable Bonds | 3 |
ethyl loflazepate (29177-84-2)
CM 6912 · ethyl flucozepate · Victan
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- Ethyl loflazepate: a prodrug from the benzodiazepine series designed to dissociate anxiolytic and sedative activities. (Drug Research, 1985)
- Quantitative analysis of CM 6912 (ethyl loflazepate) and its metabolites in plasma and urine by chemical ionization gas chromatography mass spectrometry. Application to pharmacokinetic studies in man (Journal of Mass Spectrometry, 1980)
- Analysis of the metabolites of ethyl loflazepate by gas chromatography with electron-capture detection (Journal of Chromatography B: Biomedical Sciences and Applications, 1981)
- Effects of etizolam and ethyl loflazepate on the P300 event-related potential in healthy subjects (Annals of General Psychiatry, 2010)
- Studies on the Muscle Relaxation Effects of Ethyl Loflazepate (CM6912) and Evaluation as an Anti-Anxiety Drug (Japanese Journal of Pharmacology, 1984)
- Inhibitory Effect on 3H-Diazepam Binding and Potentiating Action on GABA of Ethyl Loflazepate, a New Minor Tranquilizer (Japanese Journal of Pharmacology, 1985)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - CM 6912
- ethyl flucozepate
- Victan
-
SMILESCCOC(=O)C1C(=O)NC2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3F
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InChIKeyCUCHJCMWNFEYOM-UHFFFAOYSA-N
- Pubchem - ethyl loflazepate
- Wikipedia - ethyl loflazepate
Ethyl loflazepate (marketed under the brand names Meilax, Ronlax and Victan) is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. In animal studies it was found to have low toxicity, although in rats evidence of pulmonary phospholipidosis occurred with pulmonary foam cells developing with long-term use of very high doses.
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