| Weight | 316.382 g/mol |
|---|---|
| Formula | C16H16N2O3S |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 5 |
Febuxostat (144060-53-7)
Score:
#939 in Biochemistry
,
#2476 in Biology
,
#3090 in Chemistry
"What do you need help with?"
LabBot
- Sigma-Aldrich - Febuxostat150.00 USD
- Fisher Scientific - Search for Febuxostat
- TCI - Febuxostat84.00 - 272.00 USD
- Febuxostat Compared with Allopurinol in Patients with Hyperuricemia and Gout (The New England Journal of Medicine, 2005)
- Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: A 28week, phase III, randomized, doubleblind, parallelgroup trial (Arthritis & Rheumatism, 2008)
- The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial. (Arthritis Research & Therapy, 2010)
- Selectivity of febuxostat, a novel non-purine inhibitor of xanthine oxidase/xanthine dehydrogenase (Life Sciences, 2005)
- Febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase: a twenty-eight-day, multicenter, phase II, randomized, double-blind, placebo-controlled, dose-response clinical trial examining safety and efficacy in patients with gout. (Arthritis & Rheumatism, 2005)
- Clinical efficacy and safety of successful longterm urate lowering with febuxostat or allopurinol in subjects with gout. (The Journal of Rheumatology, 2009)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1=C(SC(=N1)C2=CC(=C(C=C2)OCC(C)C)C#N)C(=O)O
-
InChIKeyBQSJTQLCZDPROO-UHFFFAOYSA-N
- Pubchem - Febuxostat
- Wikipedia - febuxostat
Febuxostat, sold under the brand names Uloric and Adenuric, is a medication used in the treatment of chronic gout and hyperuricemia. There are concerns about more heart related deaths with febuxostat compared to allopurinol. It inhibits xanthine oxidase, thus reducing production of uric acid in the body.
Suppliers
Most-cited Publications
Areas of Application
Safety
Alternate Names
External Links
Synthesis
Reactant
+
2-Chloro-4-methylthiazole-5-carboxylic acid
(Stille)
Similar Compounds
4-methyl-2-[3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylic acid
(144059-85-8)
1 alternate name
3 suppliers
33763-20-1
(33763-20-1)
1 alternate name
3 suppliers
144060-98-0
(144060-98-0)
1 alternate name
3 suppliers
89401-54-7
(89401-54-7)
1 alternate name
3 suppliers
39091-00-4
(39091-00-4)
1 alternate name
3 suppliers
(4-methyl-2-phenyl-1,3-thiazol-5-yl)methanol
(61291-91-6)
1 alternate name
3 suppliers
34418-48-9
(34418-48-9)
1 alternate name
3 suppliers
4-methyl-2-phenyl-1,3-thiazole-5-carbohydrazide
(61292-08-8)
1 alternate name
3 suppliers
10058-38-5
(10058-38-5)
1 alternate name
3 suppliers
2-(2-methoxyphenyl)-1,3-thiazole-5-carbaldehyde
(915923-15-8)
1 alternate name
3 suppliers
2-(3-methoxyphenyl)-1,3-thiazole-5-carbaldehyde
(915923-79-4)
1 alternate name
3 suppliers
34272-67-8
(34272-67-8)
1 alternate name
3 suppliers
2-(3-pyridinyl)-5,6-dihydro-1,3-benzothiazol-7(4H)-one
(154404-89-4)
1 alternate name
3 suppliers
23353-14-2
(23353-14-2)
1 alternate name
3 suppliers
2-(3,4-dimethoxyphenyl)-1,3-thiazole-4-carboxylic Acid
(132307-22-3)
1 alternate name
3 suppliers
2-(2-methylphenyl)-1,3-thiazole-5-carbaldehyde
(915919-92-5)
1 alternate name
3 suppliers
5-(chloromethyl)-2-(2-methoxyphenyl)-1,3-thiazole hydrochloride
(1185121-67-8)
1 alternate name
3 suppliers
1-[2-(2-methoxyphenyl)-1,3-thiazol-5-yl]methanamine
(915921-26-5)
1 alternate name
3 suppliers
1-[2-(3-methylphenyl)-1,3-thiazol-4-yl]methanamine
(89152-85-2)
1 alternate name
3 suppliers
4-(chloromethyl)-2-(3-methylphenyl)-1,3-thiazole
(41963-17-1)
1 alternate name
3 suppliers
4-(chloromethyl)-2-[3-(trifluoromethyl)phenyl]-1,3-thiazole
(886629-31-8)
1 alternate name
3 suppliers
5-(chloromethyl)-2-(3-methoxyphenyl)-1,3-thiazole
(915920-12-6)
1 alternate name
3 suppliers
{[2-(3-methoxyphenyl)-1,3-thiazol-5-yl]methyl}amine dihydrochloride
(1185709-34-5)
1 alternate name
3 suppliers
2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-4-carboxylic acid hydrate
(1559059-84-5)
1 alternate name
3 suppliers
2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-4-carboxylic acid
(144061-16-5)
1 alternate name
3 suppliers
2-Phenylthiazole-5-carbaldehyde
(1011-40-1)
1 alternate name
3 suppliers
Bleomycin sulfate
(11056-06-7, 9041-93-4)
1 alternate name
3 suppliers
2-methyl-4-phenyl-1,3-thiazole-5-carboxylic Acid
(32002-72-5)
1 alternate name
3 suppliers
thiostrepton
(1393-48-2)
1 alternate name
3 suppliers
4-(4-methoxy-2,5-dimethylphenyl)-5-methyl-1,3-thiazol-2-amine
(879053-84-6)
1 alternate name
3 suppliers
10045-50-8
(10045-50-8)
1 alternate name
3 suppliers
benzyl 2-amino-4-methyl-1,3-thiazole-5-carboxylate
(692745-02-1)
1 alternate name
3 suppliers
2-(4-chlorophenyl)-1,3-thiazole-4-carboxylic Acid
(17228-98-7)
1 alternate name
3 suppliers
64399-23-1
(64399-23-1)
1 alternate name
3 suppliers
Chetomin
(1403-36-7)
1 alternate name
3 suppliers
2-Phenylthiazole-4-carboxylic Acid
(7113-10-2)
1 alternate name
3 suppliers
20287-70-1
(20287-70-1)
1 alternate name
3 suppliers
IRINOTECAN HYDROCHLORIDE Trihydrate
(136572-09-3)
1 alternate name
3 suppliers
Fenclozic acid
(17969-20-9)
1 alternate name
3 suppliers
5-(chloromethyl)-2-(2-methylphenyl)-1,3-thiazole hydrochloride
(1992995-91-1)
1 alternate name
3 suppliers
10045-52-0
(10045-52-0)
1 alternate name
3 suppliers
31877-68-6
(31877-68-6)
1 alternate name
3 suppliers
Diethyl 2-amino-1,3-thiazole-4,5-dicarboxylate
(5445-93-2)
1 alternate name
3 suppliers
4-(chloromethyl)-2-(4-methylphenyl)-1,3-thiazole
(35199-18-9)
1 alternate name
3 suppliers
methyl 2-[(chloroacetyl)amino]-4-methyl-1,3-thiazole-5-carboxylate
(6125-36-6)
1 alternate name
3 suppliers
TOPOTECAN HYDROCHLORIDE
(119413-54-6)
1 alternate name
3 suppliers
Leurosidine sulfate
(18556-44-0)
1 alternate name
3 suppliers
Rubitecan
(91421-42-0)
1 alternate name
3 suppliers
3-(4-chlorophenyl)-4-methyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxylic acid
(488804-08-6)
1 alternate name
3 suppliers
(2-phenyl-1,3-thiazol-4-yl)acetic acid hydrochloride
(857998-13-1)
1 alternate name
3 suppliers
(2-phenyl-1,3-thiazol-4-yl)acetic acid
(16441-28-4)
1 alternate name
3 suppliers
104960-56-7
(104960-56-7)
1 alternate name
3 suppliers
4-(chloromethyl)-2-(2-methylphenyl)-1,3-thiazole
(91349-33-6)
1 alternate name
3 suppliers
ATORVASTATIN CALCIUM
(110862-48-1, 134523-03-8)
1 alternate name
3 suppliers
143361-87-9
(143361-87-9)
1 alternate name
3 suppliers
Thifluzamide
(130000-40-7)
1 alternate name
3 suppliers
penitrem A
(12627-35-9)
1 alternate name
3 suppliers
[2-(4-fluorophenyl)-1,3-thiazol-4-yl]acetic acid
(17969-24-3)
1 alternate name
3 suppliers
39067-29-3
(39067-29-3)
1 alternate name
3 suppliers
69898-40-4
(69898-40-4)
1 alternate name
3 suppliers
4-(Chloromethyl)-2-(4-chlorophenyl)-1,3-thiazole
(17969-22-1)
1 alternate name
3 suppliers
7-amino-AMD
(7240-37-1)
1 alternate name
3 suppliers
63788-62-5
(63788-62-5)
1 alternate name
3 suppliers
Fendosal
(53597-27-6)
1 alternate name
3 suppliers
2-(ethylamino)-4-methyl-1,3-thiazole-5-carboxylic acid
(162651-09-4)
1 alternate name
3 suppliers
Tezosentan
(180384-57-0)
1 alternate name
3 suppliers
126643-37-6
(126643-37-6)
1 alternate name
3 suppliers
72850-76-1
(72850-76-1)
1 alternate name
3 suppliers
2-phenylthiazole-4-carbaldehyde
(20949-81-9)
1 alternate name
3 suppliers
11J-560S
(62522-87-6)
1 alternate name
3 suppliers
17279-56-0
(17279-56-0)
1 alternate name
3 suppliers
Olmesartan medoxomil
(144689-63-4)
1 alternate name
3 suppliers
Puromycin hydrochloride
(58-58-2)
1 alternate name
3 suppliers
isopropyl 2-amino-4-methyl-1,3-thiazole-5-carboxylate
(692745-01-0)
1 alternate name
3 suppliers
N-methyl-1-(2-phenyl-1,3-thiazol-5-yl)methanamine - malonic acid (1:1)
(1269226-60-9)
1 alternate name
3 suppliers
Salvianolic acid B
(121521-90-2)
1 alternate name
3 suppliers
Fumitremorgin C
(118974-02-0)
1 alternate name
3 suppliers
4-(4-methoxy-2,5-dimethylphenyl)-1,3-thiazol-2-amine
(879053-77-7)
1 alternate name
3 suppliers
ethyl 2-hydrazino-4-methyl-1,3-thiazole-5-carboxylate
(52481-66-0)
1 alternate name
3 suppliers
4-(chloromethyl)-2-phenyl-1,3-thiazole
(4771-31-7)
1 alternate name
3 suppliers
4-(chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole
(113264-13-4)
1 alternate name
3 suppliers
6340-29-0
(6340-29-0)
1 alternate name
3 suppliers
1-(2-phenyl-1,3-thiazol-4-yl)methanamine
(165736-03-8)
1 alternate name
3 suppliers
(2-phenyl-1,3-thiazol-4-yl)methylamine dihydrochloride
(89152-61-4)
1 alternate name
3 suppliers
4-(chloromethyl)-2-(2-chlorophenyl)-1,3-thiazole
(588676-51-1)
1 alternate name
3 suppliers
Rifamycin S
(13553-79-2)
1 alternate name
3 suppliers
Berberrubine chloride
(15401-69-1)
1 alternate name
3 suppliers
4-(2,4-dimethoxyphenyl)-5-methyl-1,3-thiazol-2-amine
(117844-98-1)
1 alternate name
3 suppliers
vitamin B12
(13408-78-1, 68-19-9)
1 alternate name
3 suppliers
Cyanocobalamine
(68-19-9)
1 alternate name
3 suppliers
Febuxostat
CAS Directory
