| Weight | 375.4 g/mol |
|---|---|
| Formula | C19H22FN3O4 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 4 |
Gatifloxacin (112811-59-3)
Score:
#278 in Microbiology
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#1070 in Physics
,
#2434 in Biology
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#3030 in Chemistry
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- Comparison of the antibacterial activities of the quinolones Bay 12-8039, gatifloxacin (AM 1155), trovafloxacin, clinafloxacin, levofloxacin and ciprofloxacin. (Journal of Antimicrobial Chemotherapy, 1997)
- Outpatient Gatifloxacin Therapy and Dysglycemia in Older Adults (The New England Journal of Medicine, 2006)
- Outbreak of Clostridium difficile Infection in a Long-Term Care Facility: Association with Gatifloxacin Use (Clinical Infectious Diseases, 2004)
- A phase II study of the sterilising activities of ofloxacin, gatifloxacin and moxifloxacin in pulmonary tuberculosis (International Journal of Tuberculosis and Lung Disease, 2008)
- Gatifloxacin and moxifloxacin: an in vitro susceptibility comparison to levofloxacin, ciprofloxacin, and ofloxacin using bacterial keratitis isolates (American Journal of Ophthalmology, 2003)
- Rates of Torsades de Pointes Associated with Ciprofloxacin, Ofloxacin, Levofloxacin, Gatifloxacin, and Moxifloxacin (Pharmacotherapy, 2001)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F
-
InChIKeyXUBOMFCQGDBHNK-UHFFFAOYSA-N
- Pubchem - Gatifloxacin
- Wikipedia - gatifloxacin anhydrous
Gatifloxacin sold under the brand names Gatiflo, Tequin and Zymar, is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. Bristol-Myers Squibb introduced Gatifloxacin in 1999 under the proprietary name Tequin for the treatment of respiratory tract infections, having licensed the medication from Kyorin Pharmaceutical Company of Japan. Allergan produces it in eye-drop formulation under the names Zymar and Zymaxid.
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