| Weight | 623.15 g/mol |
|---|---|
| Formula | C33H39ClN4O6 |
| Hydrogen Acceptors | 9 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 4 |
Irinotecan hydrochloride (100286-90-6)
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- Involvement of -Glucuronidase in Intestinal Microflora in the Intestinal Toxicity of the Antitumor Camptothecin Derivative Irinotecan Hydrochloride (CPT-11) in Rats (Cancer Research, 1996)
- Phase I-II study of irinotecan hydrochloride combined with cisplatin in patients with advanced gastric cancer (Journal of Clinical Oncology, 1997)
- [Late phase II study of irinotecan hydrochloride (CPT-11) in advanced gastric cancer. CPT-11 Gastrointestinal Cancer Study Group]. (Gan to kagaku ryoho. Cancer & chemotherapy, 1994)
- Inhibition of intestinal microflora -glucuronidase modifies the distribution of the active metabolite of the antitumor agent, irinotecan hydrochloride (CPT-11) in rats (Cancer Chemotherapy and Pharmacology, 1998)
- Protective Effects of Kampo Medicines and Baicalin against Intestinal Toxicity of a New Anticancer Camptothecin Derivative, Irinotecan Hydrochloride (CPT-11), in Rats (Japanese Journal of Cancer Research, 1995)
- Cell Cycle-Dependent Chronotoxicity of Irinotecan Hydrochloride in Mice (Journal of Pharmacology and Experimental Therapeutics, 1997)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7.Cl
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InChIKeyGURKHSYORGJETM-UHFFFAOYSA-N
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