| Weight | 553.571 g/mol |
|---|---|
| Formula | C29H42Cl2N2O4 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 7 |
EMETINE DIHYDROCHLORIDE (83029-37-2, 316-42-7)
Emetine · Emetine Hydrochloride · Methylcephaeline
Score:
#1327 in Biochemistry
,
#3239 in Biology
,
#4048 in Chemistry
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- Structural basis for inhibition of protein synthesis by emetine and cycloheximide based on an analogy between ipecac alkaloids and glutarimide antibiotics. (Proceedings of the National Academy of Sciences of the United States of America, 1966)
- ON A NEW AEROBIC METABOLITE WHOSE PRODUCTION BY BRAIN IS INHIBITED BY APOMORPHINE, EMETINE, ERGOTAMINE, EPINEPHRINE, AND MENADIONE (Journal of Pharmacology and Experimental Therapeutics, 1944)
- Inhibitors of Protein Biosynthesis V. EFFECTS OF EMETINE ON PROTEIN AND NUCLEIC ACID BIOSYNTHESIS IN HeLa CELLS (Journal of Biological Chemistry, 1968)
- Emetine allows identification of origins of mammalian DNA replication by imbalanced DNA synthesis, not through conservative nucleosome segregation. (The EMBO Journal, 1991)
- Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine (eLife, 2014)
- Enantioselective Total Syntheses of the Ipecacuanha Alkaloid Emetine, the Alangium Alkaloid Tubulosine and a Novel Benzoquinolizidine Alkaloid by Using a Domino Process (Chemistry: A European Journal, 2004)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Emetine
- Emetine Hydrochloride
- Methylcephaeline
- Ipecine
-
SMILESCCC1CN2CCC3=CC(=C(C=C3C2CC1CC4C5=CC(=C(C=C5CCN4)OC)OC)OC)OC.Cl.Cl
-
InChIKeyJROGBPMEKVAPEH-UHFFFAOYSA-N
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