| Weight | 479.279 g/mol |
|---|---|
| Formula | C21H27Cl4N3O |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 9 |
Acridine mustard (146-59-8)
ICR-170 · ICR 170
Score:
#56 in Molecular and cellular biology
,
#1740 in Biochemistry
,
#3841 in Biology
,
#4838 in Chemistry
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- DNA-directed alkylating agents. 1. Structure-activity relationships for acridine-linked aniline mustards: consequences of varying the reactivity of the mustard. (Journal of Medicinal Chemistry, 1990)
- The mutagenicity of the acridine mustard (ICR-170) and the structurally related compounds in Neurosopora (Mutation Research, 1967)
- Alleviation of mutagenic effects of polycyclic aromatic agents (quinacrine mustard, ICR-191 and ICR-170) by caffeine and pentoxifylline (Mutation Research, 2003)
- The mutagenic activity of ICR-170 in Saccharomyces cerevisiae (Mutation Research, 1970)
- Potent antitumor 9-anilinoacridines and acridines bearing an alkylating N-mustard residue on the acridine chromophore: Synthesis and biological activity (Journal of Medicinal Chemistry, 2006)
- In situ localization and characterization of different classes of chromosomal DNA: acridine orange and quinacrine mustard fluorescence (Chromosoma, 1973)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - ICR-170
- ICR 170
-
SMILESCCN(CCCNC1=C2C=C(C=CC2=NC3=C1C=CC(=C3)Cl)OC)CCCl.Cl.Cl
-
InChIKeyPWGOWIIEVDAYTC-UHFFFAOYSA-N
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