| Weight | 413.426 g/mol |
|---|---|
| Formula | C22H23NO7 |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 4 |
noscapine
Narcotine · Noscapine Hydrochloride · Dreluso Brand of Noscapine Hydrochloride
6035-40-1, 128-62-1, 912-60-7
Score:
#1044 in Biochemistry
,
#3382 in Chemistry
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- Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells (Proceedings of the National Academy of Sciences of the United States of America, 1998)
- A Papaver somniferum 10-Gene Cluster for Synthesis of the Anticancer Alkaloid Noscapine (Science, 2012)
- Brominated Derivatives of Noscapine Are Potent Microtubule-interfering Agents That Perturb Mitosis and Inhibit Cell Proliferation (Molecular Pharmacology, 2003)
- Noscapine Alters Microtubule Dynamics in Living Cells and Inhibits the Progression of Melanoma (Cancer Research, 2002)
- Paclitaxel-resistant human ovarian cancer cells undergo c-Jun NH2-terminal kinase-mediated apoptosis in response to noscapine (Journal of Biological Chemistry, 2002)
- Noscapine Crosses the Blood-Brain Barrier and Inhibits Glioblastoma Growth (Clinical Cancer Research, 2004)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H302: Harmful if swallowed
Warning Acute toxicity, oral - Category 4 - Narcotine
- Noscapine Hydrochloride
- Dreluso Brand of Noscapine Hydrochloride
- Berna Brand of Noscapine Hydrochloride
- Librochin prikkelhoest
- Capval
- Boots Brand of Noscapine Hydrochloride
- Noscapect
- Capval Tropfen
- Noscapine Dreluso Brand
- Noscapine Hydrogen Embonate
- Tuscalman
- Byk Brand of Noscapine Hydrochloride
- Dreluso Brand of Noscapine
-
SMILESCN1CCC2=CC3=C(C(=C2C1C4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)OC)OCO3
-
InChIKeyAKNNEGZIBPJZJG-UHFFFAOYSA-N
- Pubchem - noscapine
- Wikipedia - 6,7-dimethoxy-3-(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-3H-isobenzofuran-1-one
Noscapine (also known as Narcotine, Nectodon, Nospen, Anarcotine and (archaic) Opiane) is a benzylisoquinoline alkaloid from plants of the poppy family, without painkilling properties. This agent is primarily used for its antitussive (cough-suppressing) effects.
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noscapine
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