| Weight | 301.386 g/mol |
|---|---|
| Formula | C18H23NO3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 7 |
isoxsuprine (395-28-8)
Isoxsuprine Hydrochloride · Duvadilan
Score:
#1763 in Biochemistry
,
#3876 in Biology
,
#4881 in Chemistry
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- Isoxsuprine-induced release of pulmonary surfactant in the rabbit fetus (American Journal of Obstetrics and Gynecology, 1977)
- Isoxsuprine-induced alterations of pulmonary pressure-volume relationships in premature rabbits (American Journal of Obstetrics and Gynecology, 1974)
- The pharmacologic control of excessive uterine activity with isoxsuprine (American Journal of Obstetrics and Gynecology, 1961)
- Prenatal and postnatal isoxsuprine and respiratory-distress syndrome. (The Lancet, 1973)
- Effects of maternal isoxsuprine administration on preterm infants. (The Journal of Pediatrics, 1979)
- The Effect of Oral Isoxsuprine and Pentoxifylline on Digital and Laminar Blood Flow in Healthy Horses (Veterinary Surgery, 1999)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Isoxsuprine Hydrochloride
- Duvadilan
-
SMILESCC(COC1=CC=CC=C1)NC(C)C(C2=CC=C(C=C2)O)O
-
InChIKeyBMUKKTUHUDJSNZ-UHFFFAOYSA-N
- Pubchem - isoxsuprine
- Wikipedia - 4-[1-hydroxy-2-(1-phenoxypropan-2-ylamino)propyl]phenol
Isoxsuprine (used as isoxsuprine hydrochloride) is a drug used as a vasodilator in humans (under the trade name Duvadilan) and equines. Isoxsuprine is a 2 adrenoreceptor agonist that causes direct relaxation of uterine and vascular smooth muscle via 2 receptors.
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Synthesis
Reactant
+
4-CHLOROPHENOL
(Grignard alcohol)
Phenol
+
Reactant
(Williamson ether)
benzaldehyde
+
Reactant
(Dakin oxidation)
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