| Weight | 395.434 g/mol |
|---|---|
| Formula | C22H22FN3O3 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 5 |
Ketanserin (83846-83-7, 74050-98-9)
R 41468 · R-41468 · R-41,468
Score:
#801 in Neuroscience
,
#3511 in Biology
,
#4397 in Chemistry
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- [3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role. (Molecular Pharmacology, 1982)
- Molecular pharmacology of 5-HT1 and 5-HT2 recognition sites in rat and pig brain membranes: Radioligand binding studies with [3H]5-HT, [3H]8-OH-DPAT, ()[125I]iodocyanopindolol, [3H]mesulergine and [3H]Ketanserin (European Journal of Pharmacology, 1985)
- Vascular effects of ketanserin (R 41 468), a novel antagonist of 5-HT2 serotonergic receptors. (Journal of Pharmacology and Experimental Therapeutics, 1981)
- Mechanism of the hypotensive effect of ketanserin. (Journal of Cardiovascular Pharmacology, 1982)
- Psychological and Physiological Effects of MDMA (Ecstasy) after Pretreatment with the 5-HT2 Antagonist Ketanserin in Healthy Humans (Neuropsychopharmacology, 2000)
- Inhibition of 5-hydroxytryptamine-induced and-amplified human platelet aggregation by ketanserin (R 41 468), a selective 5-HT2-receptor antagonist (Inflammation Research, 1982)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - R 41468
- R-41468
- R-41,468
- R41,468
- R41468
- 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione
- R 41,468
-
SMILESC1CN(CCC1C(=O)C2=CC=C(C=C2)F)CCN3C(=O)C4=CC=CC=C4NC3=O
-
InChIKeyFPCCSQOGAWCVBH-UHFFFAOYSA-N
- Pubchem - Ketanserin
- Wikipedia - ketanserin
Ketanserin (INN, USAN, BAN) (brand name Sufrexal; former developmental code name R41468) is a drug used clinically as an antihypertensive agent and in scientific research to study the serotonin system; specifically, the 5-HT2 receptor family. It was discovered at Janssen Pharmaceutica in 1980.
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