| Weight | 1209.421 g/mol |
|---|---|
| Formula | C59H84N16O12 |
| Hydrogen Acceptors | 14 |
| Hydrogen Donors | 15 |
| Aromatic Rings | 4 |
| Rotatable Bonds | 32 |
Leuprorelin (53714-56-0, 74381-53-6)
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- One- and three-month release injectable microspheres of the LH-RH superagonist leuprorelin acetate. (Advanced Drug Delivery Reviews, 1997)
- Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy (Nature Medicine, 2003)
- Preparation of Three-Month Depot Injectable Microspheres of Leuprorelin Acetate Using Biodegradable Polymers (Pharmaceutical Research, 1994)
- Phase 2 trial of leuprorelin in patients with spinal and bulbar muscular atrophy. (Annals of Neurology, 2009)
- Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study): a multicentre, randomised, double-blind, placebo-controlled trial (Lancet Neurology, 2010)
- Leuprorelin : a review of its pharmacology and therapeutic use in prostatic cancer, endometriosis and other sex hormone-related disorders (Drugs, 1994)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCNC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(=O)N6
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- Pubchem - Leuprorelin
- Wikipedia - leuprolide
Leuprorelin, also known as leuprolide, is a manufactured version of a hormone used to treat prostate cancer, breast cancer, endometriosis, uterine fibroids, and early puberty. It is given by injection into a muscle or under the skin. Common side effects include hot flashes, unstable mood, trouble sleeping, headaches, and pain at the site of injection.
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