Weight | 259.136 g/mol |
---|---|
Formula | C11H12Cl2N2O |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 1 |
Aromatic Rings | 1 |
Rotatable Bonds | 3 |
Lofexidine (31036-80-3)
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- Effects of THC and Lofexidine in a Human Laboratory Model of Marijuana Withdrawal and Relapse (Psychopharmacology, 2008)
- Randomised double-blind comparison of lofexidine and methadone in the in-patient treatment of opiate withdrawal. (Drug and Alcohol Dependence, 1996)
- Effects of lofexidine on stress-induced and cue-induced opioid craving and opioid abstinence rates: preliminary findings (Psychopharmacology, 2007)
- Alcohol withdrawal syndromes: clinical management with lofexidine (Alcoholism: Clinical and Experimental Research, 1985)
- Repeated Lofexidine Treatment Attenuates Stress-Induced, But not Drug Cues-Induced Reinstatement of a Heroin-Cocaine Mixture (Speedball) Seeking in Rats (Neuropsychopharmacology, 2001)
- Double-blind study of lofexidine and clonidine in the detoxification of opiate addicts in hospital (Drug and Alcohol Dependence, 1997)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(C1=NCCN1)OC2=C(C=CC=C2Cl)Cl
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InChIKeyKSMAGQUYOIHWFS-UHFFFAOYSA-N
- Pubchem - Lofexidine
- Wikipedia - lofexidine
Lofexidine (sold under the brand names: BritLofex and Kai Er Ding) is an 2A adrenergic receptor agonist, historically used as an antihypertensive, but more commonly used to alleviate the physical symptoms of heroin and other types of opioid withdrawal.
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