| Weight | 404.547 g/mol |
|---|---|
| Formula | C24H36O5 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 6 |
lovastatin (75330-75-5)
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#213 in Neuroscience
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#258 in Biochemistry
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#990 in Biology
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#1097 in Chemistry
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- Primary Prevention of Acute Coronary Events With Lovastatin in Men and Women With Average Cholesterol Levels: Results of AFCAPS/TexCAPS (JAMA, 1998)
- Comparative dose efficacy study of atorvastatin versus simvastatin, pravastatin, lovastatin, and fluvastatin in patients with hypercholesterolemia (the CURVES study) (American Journal of Cardiology, 1998)
- Effect of lovastatin on early carotid atherosclerosis and cardiovascular events. Asymptomatic Carotid Artery Progression Study (ACAPS) Research Group. (Circulation, 1994)
- Coronary angiographic changes with lovastatin therapy. The Monitored Atherosclerosis Regression Study (MARS). (Annals of Internal Medicine, 1993)
- Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages. (Journal of Clinical Investigation, 1997)
- Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors (Nature Reviews Drug Discovery, 2003)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C
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InChIKeyPCZOHLXUXFIOCF-UHFFFAOYSA-N
- Pubchem - lovastatin
- Wikipedia - lovastatin
Lovastatin (Merck's Mevacor) is a statin drug, used for lowering cholesterol in those with hypercholesterolemia to reduce risk of cardiovascular disease. Lovastatin is a naturally occurring compound found in low concentrations in food such as oyster mushrooms, red yeast rice, and Pu-erh.
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lovastatin
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