| Weight | 511.152 g/mol |
|---|---|
| Formula | C17H8Cl2F8N2O3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 5 |
Lufenuron (103055-07-8)
Score:
#4 in Veterinary medicine
,
#15 in Animal science
,
#22 in Zoology
,
#3253 in Biology
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- Cyp12a4 confers lufenuron resistance in a natural population of Drosophila melanogaster (Proceedings of the National Academy of Sciences of the United States of America, 2005)
- Effect of the insecticides abamectin and lufenuron on eggs and larvae of Chrysoperla externa under laboratory conditions (Biocontrol, 2004)
- Lufenuron, a chitin-synthesis inhibitor, interrupts development of Drosophila melanogaster (Journal of Experimental Zoology, 1997)
- Comparative Effects of Two Chitin Synthesis Inhibitors, Hexaflumuron and Lufenuron, in a Bait Matrix Against Subterranean Termites (Isoptera: Rhinotermitidae) (Journal of Economic Entomology, 1996)
- Efficacy of lufenuron as chemosterilant against Ceratitis capitata in field trials (Pest Management Science, 2004)
- Dissipation Behavior of Lufenuron, Benzoylphenylurea Insecticide, in/on Chinese Cabbage Applied by Foliar Spraying Under Greenhouse Conditions (Bulletin of Environmental Contamination and Toxicology, 2008)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H317: May cause an allergic skin reaction
Warning Sensitization, Skin - Category 1 - H361: Suspected of damaging fertility or the unborn child
Warning Reproductive toxicity - Category 2 - H410: Very toxic to aquatic life with long lasting effects
Warning Hazardous to the aquatic environment, long-term hazard - Category 1 -
SMILESC1=CC(=C(C(=C1)F)C(=O)NC(=O)NC2=CC(=C(C=C2Cl)OC(C(C(F)(F)F)F)(F)F)Cl)F
-
InChIKeyPWPJGUXAGUPAHP-UHFFFAOYSA-N
- Pubchem - Lufenuron
- Wikipedia - lufenuron
Lufenuron is the active ingredient in the veterinary flea control medication Program, and one of the two active ingredients in the flea, heartworm, ringworm and anthelmintic medicine milbemycin oxime/lufenuron (Sentinel). Lufenuron is stored in the animal's body fat and transferred to adult fleas through the host's blood when they feed. Adult fleas transfer it to their growing eggs through their blood, and to hatched larvae feeding on their excrement.
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Synthesis
Reactant
+
2,6-Difluorobenzamide
(Schotten-Baumann amide from acid)
Reactant
+
2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline
(Thiourea)
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Lufenuron
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