| Weight | 211.261 g/mol |
|---|---|
| Formula | C11H17NO3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 4 |
metaproterenol (586-06-1)
Alupent · Metaproterenol Sulfate · Metaprel
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- Comparison of the anticholinergic bronchodilator ipratropium bromide with metaproterenol in chronic obstructive pulmonary disease: A 90-day multi-center study (The American Journal of Medicine, 1986)
- Airway reactivity in infants: a positive response to methacholine and metaproterenol (Journal of Applied Physiology, 1987)
- A Comparison of the Effects of Ipratropium Bromide and Metaproterenol Sulfate in Acute Exacerbations of COPD (Chest, 1990)
- The effect of sequential inhalations of metaproterenol aerosol in asthma (The Journal of Allergy and Clinical Immunology, 1980)
- Use of bronchial provocation with histamine to compare the pharmacodynamics of inhaled albuterol and metaproterenol in patients with asthma (The Journal of Allergy and Clinical Immunology, 1987)
- Comparison of the anticholinergic bronchodilator ipratropium bromide with metaproterenol in chronic obstructive pulmonary disease: Tashkin DP, Ashutosh K, Bleecker ER, et al Am J Med 81 (suppl 5A):8190 Nov 1986 (Annals of Emergency Medicine, 1987)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Alupent
- Metaproterenol Sulfate
- Metaprel
- Orciprenaline
- Orciprenaline Sulfate
- Astmopent
- Metaproterenol Polistirex
- Alotec
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SMILESCC(C)NCC(C1=CC(=CC(=C1)O)O)O
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InChIKeyLMOINURANNBYCM-UHFFFAOYSA-N
- Pubchem - metaproterenol
- Wikipedia - metaproterenol
Orciprenaline, also known as metaproterenol, is a bronchodilator used in the treatment of asthma. Orciprenaline is a moderately selective 2 adrenergic receptor agonist that stimulates receptors of the smooth muscle in the lungs, uterus, and vasculature supplying skeletal muscle, with minimal or no effect on adrenergic receptors. The pharmacologic effects of adrenergic agonist drugs, such as orciprenaline, are at least in part attributable to stimulation through adrenergic receptors of intracellular adenylyl cyclase, the enzyme which catalyzes the conversion of ATP to cAMP.
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Synthesis
Reactant
+
2-CHLOROPROPANE
(Alkylation of primary amines)
Reactant
+
ISOPROPYLAMINE
(Reductive amination)
resorcinol
+
Reactant
(Friedel-Crafts alkylation)
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