| Weight | 233.311 g/mol |
|---|---|
| Formula | C14H19NO2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 3 |
methylphenidate (113-45-1)
Ritalin · Concerta · Methylphenidate Hydrochloride
Score:
#34 in Neurology
,
#181 in Neuroscience
,
#860 in Biology
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- Physiologic, subjective, and behavioral effects of amphetamine, methamphetamine, ephedrine, phenmetrazine, and methylphenidate in man (Clinical Pharmacology & Therapeutics, 1971)
- Dopamine Transporter Occupancies in the Human Brain Induced by Therapeutic Doses of Oral Methylphenidate (American Journal of Psychiatry, 1998)
- Selective effects of methylphenidate in attention deficit hyperactivity disorder: A functional magnetic resonance study (Proceedings of the National Academy of Sciences of the United States of America, 1998)
- Therapeutic Doses of Oral Methylphenidate Significantly Increase Extracellular Dopamine in the Human Brain (The Journal of Neuroscience, 2001)
- Effects of methylphenidate on extracellular dopamine, serotonin, and norepinephrine: comparison with amphetamine. (Journal of Neurochemistry, 2002)
- Increased striatal dopamine transporter in adult patients with attention deficit hyperactivity disorder: effects of methylphenidate as measured by single photon emission computed tomography. (Neuroscience Letters, 2000)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Ritalin
- Concerta
- Methylphenidate Hydrochloride
- Metadate
- Methylin
- Ritalin SR
- Daytrana
- Mallinckrodt Brand of Methylphenidate Hydrochloride
- Celltech Brand of Methylphenidate Hydrochloride
- Centedrin
- Cephalon Brand of Methylphenidate Hydrochloride
- Novartis Brand 2 of Methylphenidate Hydrochloride
- Phenidylate
- Ritaline
- Tsentedrin
- Novartis Brand 1 of Methylphenidate Hydrochloride
- Equasym
- Ritalin-SR
-
SMILESCOC(=O)C(C1CCCCN1)C2=CC=CC=C2
-
InChIKeyDUGOZIWVEXMGBE-UHFFFAOYSA-N
- Pubchem - methylphenidate
- Wikipedia - methylphenidate
Methylphenidate, sold under various trade names, Ritalin being one of the most commonly known, is a central nervous system (CNS) stimulant of the phenethylamine and piperidine classes that is used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. The original patent was owned by CIBA, now Novartis Corporation. It was first licensed by the US Food and Drug Administration (FDA) in 1955 for treating what was then known as hyperactivity.
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Alternate Names
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Synthesis
benzene
+
Reactant
(Friedel-Crafts alkylation)
Similar Compounds
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Carbaryl
(27636-33-5, 3197-92-0, 63-25-2)
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(77-83-8, 19464-95-0)
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(92-52-4, 68409-73-4)
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FENOXYCARB
(72490-01-8)
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ISOPROPYLBIPHENYL
(19486-60-3, 25640-78-2)
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(92-59-1)
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methyl 2-benzamidoacetate
(1205-08-9)
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1,3-diphenylpropan-1-one
(1083-30-3)
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Methyl cinnamate
(1754-62-7, 103-26-4)
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Dimethylbenzylcarbinyl acetate
(151-05-3)
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3 suppliers
2-Phenylphenol
(61788-42-9, 90-43-7)
19 alternate names
3 safety hazards
3 suppliers
Pethidine hydrochloride
(50-13-5)
19 alternate names
3 suppliers
Diphenyl oxide
(101-84-8)
19 alternate names
2 safety hazards
3 suppliers
1,2-DIPHENYLHYDRAZINE
(122-66-7, 38622-18-3)
19 alternate names
5 safety hazards
3 suppliers
Diphenylamine
(68442-68-2, 122-39-4)
19 alternate names
6 safety hazards
3 suppliers
azobenzene
(103-33-3, 17082-12-1, 1080-16-6)
19 alternate names
6 safety hazards
3 suppliers
methapyrilene
(91-80-5)
19 alternate names
3 suppliers
Diphenylmethane
(101-81-5)
19 alternate names
3 suppliers
101-72-4
(101-72-4)
19 alternate names
5 safety hazards
3 suppliers
trans-Stilbene
(103-30-0, 588-59-0)
19 alternate names
3 suppliers
2-Aminobiphenyl
(90-41-5)
19 alternate names
4 safety hazards
3 suppliers
ACETOACETANILIDE
(102-01-2, 86349-51-1)
19 alternate names
3 suppliers
Benzyl ether
(103-50-4)
19 alternate names
3 safety hazards
3 suppliers
2-Phenylethyl propionate
(122-70-3)
19 alternate names
3 suppliers
Dibenzyl sulfide
(538-74-9)
19 alternate names
3 suppliers
METAMITRON
(41394-05-2)
19 alternate names
2 safety hazards
3 suppliers
Diazoaminobenzene
(136-35-6)
19 alternate names
3 suppliers
Iofendylate
(99-79-6)
19 alternate names
3 suppliers
Benzalacetone
(1896-62-4, 122-57-6)
19 alternate names
3 suppliers
cis-Stilbene
(645-49-8)
19 alternate names
3 suppliers
Chalcone
(614-47-1, 94-41-7)
19 alternate names
3 suppliers
2-Acetylnaphthalene
(93-08-3)
19 alternate names
3 suppliers
METHYL PHENYLACETATE
(101-41-7)
19 alternate names
3 suppliers
1-PHENYL-1,2-PROPANEDIONE
(579-07-7)
19 alternate names
3 suppliers
Phenethyl acetate
(103-45-7)
19 alternate names
3 suppliers
MPTP
(28289-54-5)
19 alternate names
3 suppliers
2-Fluorobiphenyl
(321-60-8)
19 alternate names
3 suppliers
p-Isopropoxydiphenylamine
(101-73-5)
19 alternate names
3 suppliers
1,2-Diphenylethane
(103-29-7, 38888-98-1)
19 alternate names
3 suppliers
Gramine
(87-52-5)
19 alternate names
3 suppliers
Ethyl phenylpropiolate
(2216-94-6)
19 alternate names
3 suppliers
N,N'-Diphenylmethylenediamine
(101-77-9, 622-14-0)
19 alternate names
3 suppliers
10094-34-5
(10094-34-5)
19 alternate names
3 suppliers
Fonofos
(944-22-9, 62680-03-9)
19 alternate names
5 safety hazards
3 suppliers
2-Acetamidofluorene
(53-96-3)
19 alternate names
3 suppliers
2-CHLOROBIPHENYL
(27323-18-8, 11097-69-1, 2051-60-7, 53469-21-9)
19 alternate names
3 suppliers
Glycidyl phenyl ether
(71031-03-3, 122-60-1)
19 alternate names
7 safety hazards
3 suppliers
rac Cotinine
(15569-85-4, 486-56-6)
19 alternate names
3 suppliers
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