| Weight | 301.302 g/mol |
|---|---|
| Formula | C15H15N3O4 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 2 |
Milrinone lactate (100286-97-3)
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- Hemodynamic Effects of IV Milrinone Lactate in Pediatric Patients With Septic Shock: A Prospective, Double-Blinded, Randomized, Placebo-Controlled, Interventional Study (Chest, 1996)
- Pharmacokinetics and pharmacodynamics of milrinone lactate in pediatric patients with septic shock (The Journal of Pediatrics, 1998)
- Stability of milrinone lactate in the presence of 29 critical care drugs and 4 i.v. solutions (American Journal of Health-system Pharmacy, 1999)
- Physical compatibility of milrinone lactate injection with intravenous drugs commonly used in the pediatric intensive care unit. (American Journal of Health-system Pharmacy, 2002)
- Assessment of inotropic and vasodilating effects of milrinone lactate in patients with dilated cardiomyopathy and severe heart failure (Arquivos Brasileiros De Cardiologia, 1999)
- Stability of Milrinone Lactate in 5% Dextrose Injection and 0.9% Sodium Chloride Injection at Concentrations of 400, 600, 800 mcg/mL (International journal of pharmaceutical compounding, 1998)
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- Pubchem - Milrinone lactate
- Wikipedia - milrinone lactate
Milrinone, commonly known and marketed under the brand name Primacor, is a medication used in patients who have heart failure. It is a phosphodiesterase 3 inhibitor that works to increase the heart's contractility and decrease pulmonary vascular resistance. Milrinone also works to vasodilate which helps alleviate increased pressures (afterload) on the heart, thus improving its pumping action.
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Synthesis
ISONICOTINIC ACID
+
Reactant
(Decarboxylative coupling)
4-BROMOPYRIDINE
+
Reactant
(Stille)
Reactant
+
4-CHLOROPYRIDINE
(Suzuki)
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