| Weight | 315.413 g/mol |
|---|---|
| Formula | C19H25NO3 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 5 |
Mitiglinide (145375-43-5, 207844-01-7)
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- The effects of mitiglinide (KAD-1229), a new anti-diabetic drug, on ATP-sensitive K+ channels and insulin secretion: comparison with the sulfonylureas and nateglinide (European Journal of Pharmacology, 2001)
- Effects of mitiglinide (S 21403) on Kir6.2/SUR1, Kir6.2/SUR2A and Kir6.2/SUR2B types of ATP-sensitive potassium channel (British Journal of Pharmacology, 2001)
- Effects of S21403 (mitiglinide) on postprandial generation of oxidative stress and inflammation in type 2 diabetic patients (Diabetologia, 2005)
- Nateglinide and mitiglinide, but not sulfonylureas, induce insulin secretion through a mechanism mediated by calcium release from endoplasmic reticulum (Journal of Pharmacology and Experimental Therapeutics, 2007)
- Carboxyl-glucuronidation of mitiglinide by human UDP-glucuronosyltransferases (Biochemical Pharmacology, 2007)
- Postprandial hyperglycemia and endothelial function in type 2 diabetes: focus on mitiglinide (Cardiovascular Diabetology, 2012)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1CCC2CN(CC2C1)C(=O)CC(CC3=CC=CC=C3)C(=O)O
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InChIKeyWPGGHFDDFPHPOB-UHFFFAOYSA-N
- Pubchem - Mitiglinide
- Wikipedia - mitiglinide
Mitiglinide (INN, trade name Glufast) is a drug for the treatment of type 2 diabetes. Mitiglinide belongs to the meglitinide (glinide) class of blood glucose-lowering drugs and is currently co-marketed in Japan by Kissei and Takeda. The North America rights to mitiglinide are held by Elixir Pharmaceuticals.
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