| Weight | 144.126 g/mol |
|---|---|
| Formula | C6H8O4 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 3 |
Monoethyl maleate
diethyl maleate · diethylmaleate · ethyl maleate
69278-94-0, 2459-05-4, 3990-03-2, 68987-59-7
Score:
#2296 in Biochemistry
,
#4594 in Biology
,
#5824 in Chemistry
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- Liver glutathione depletion induced by bromobenzene, iodobenzene, and diethylmaleate poisoning and its relation to lipid peroxidation and necrosis. (American Journal of Pathology, 1985)
- Induction of cystine and glutamate transport activity in human fibroblasts by diethyl maleate and other electrophilic agents. (Journal of Biological Chemistry, 1984)
- Cellular glutathione depletion by diethyl maleate or buthionine sulfoximine: no effect of glutathione depletion on the oxygen enhancement ratio (Radiation Research, 1983)
- Inhibition and enhancement of microsomal drug metabolism by diethyl maleate (Biochemical Pharmacology, 1978)
- Effect on the K/sub m/ for radiosensitization at 0/sup 0/C of thiol depletion by diethylmaleate pretreatment: quantitative differences found using the radiation sensitizing agent misonidazole or oxygen (Radiation Research, 1984)
- Diethylmaleate activates the transcription factor Pap1 by covalent modification of critical cysteine residues (Molecular Microbiology, 2002)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - diethyl maleate
- diethylmaleate
- ethyl maleate
- diethyl maleic acid diester
- maleic acid diethyl ester
-
SMILESCCOC(=O)C=CC(=O)O
-
InChIKeyXLYMOEINVGRTEX-UHFFFAOYSA-N
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Synthesis
Reactant
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
Reactant
+
1-Hydroxy-1,2-benziodoxol-3(1H)-one 1-oxide
(Nicolaou IBX dehydrogenation)
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Monoethyl maleate
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