mycophenolic acid (483-60-3, 24280-93-1)

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Suppliers

• Sigma-Aldrich - mycophenolic acid
  73.40 - 280.00 USD
• Fisher Scientific - Search for mycophenolic acid
• TCI - mycophenolic acid
  108.00 USD

Most-cited Publications

• Lymphocyte-selective cytostatic and immunosuppressive effects of mycophenolic acid in vitro: role of deoxyguanosine nucleotide depletion. (Scandinavian Journal of Immunology, 1991)
• Structure and Mechanism of Inosine Monophosphate Dehydrogenase in Complex with the Immunosuppressant Mycophenolic Acid (Cell, 1996)
• Immunosuppressive and other effects of mycophenolic acid and an ester prodrug, mycophenolate mofetil. (Immunological Reviews, 1993)
• Comparison of the effects of tacrolimus and cyclosporine on the pharmacokinetics of mycophenolic acid. (Therapeutic Drug Monitoring, 2001)
• The inhibition of nucleic acid synthesis by mycophenolic acid (Biochemical Journal, 1969)
• Mycophenolic acid binding to human serum albumin: characterization and relation to pharmacodynamics. (Clinical Chemistry, 1995)

Areas of Application

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Trends

Alternate Names

• mycophenolate mofetil
• Cellcept
• myfortic
• Mycophenolate Sodium
• RS 61443
• mycophenolate mofetil hydrochloride
• RS-61443
• mycophenolic acid morpholinoethyl ester
• Sodium Mycophenolate
• Mofetil, Mycophenolate
• Mofetil Hydrochloride, Mycophenolate
• RS61443
• SMILES
  CC1=C(C(=C(C2=C1COC2=O)O)CC=C(C)CCC(=O)O)OC
• InChIKey
  HPNSFSBZBAHARI-UHFFFAOYSA-N

External Links

• Pubchem - mycophenolic acid
• Wikipedia - mycophenolic acid
  Mycophenolic acid, less accurately called mycophenolate, is an immunosuppressant drug used to prevent rejection in organ transplantation. It inhibits an enzyme needed for the growth of T cells and B cells. It was initially marketed as the prodrug mycophenolate mofetil (MMF) to improve oral bioavailability.

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