| Weight | 265.353 g/mol |
|---|---|
| Formula | C15H23NO3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 9 |
oxprenolol
Trasicor · Oxprenolol Hydrochloride · Koretal
22972-98-1, 6452-71-7, 22972-96-9
Score:
#596 in Neuroscience
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#1035 in Biochemistry
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- ELECTROCARDIOGRAM, PLASMA CATECHOLAMINES AND LIPIDS, AND THEIR MODIFICATION BY OXPRENOLOL WHEN SPEAKING BEFORE AN AUDIENCE (The Lancet, 1973)
- Randomised comparison of methyldopa and oxprenolol for treatment of hypertension in pregnancy. (BMJ, 1979)
- A long-term prevention study with oxprenolol in coronary heart disease. (The New England Journal of Medicine, 1982)
- EFFECT OF OXPRENOLOL ON STAGE-FRIGHT IN MUSICIANS (The Lancet, 1977)
- Simplified method for the determination of oxprenolol and other -receptor blocking agents in biological fluids by gas-liquid chromatography (Journal of Chromatography A, 1976)
- Randomised controlled comparative study of methyldopa and oxprenolol in treatment of hypertension in pregnancy. (BMJ, 1983)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Trasicor
- Oxprenolol Hydrochloride
- Koretal
- Tevacor
- Slow Trasicor
- Coretal
-
SMILESCC(C)NCC(COC1=CC=CC=C1OCC=C)O
-
InChIKeyCEMAWMOMDPGJMB-UHFFFAOYSA-N
- Pubchem - oxprenolol
- Wikipedia - oxprenolol
Oxprenolol (brand names Trasacor, Trasicor, Coretal, Laracor, Slow-Pren, Captol, Corbeton, Slow-Trasicor, Tevacor, Trasitensin, Trasidex) is a non-selective beta blocker with some intrinsic sympathomimetic activity. It is used for the treatment of angina pectoris, abnormal heart rhythms and high blood pressure. Oxprenolol is a lipophilic beta blocker which passes the bloodbrain barrier more easily than water-soluble beta blockers.
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Synthesis
Reactant
+
1-Hydroxy-1,2-benziodoxol-3(1H)-one 1-oxide
(Nicolaou IBX dehydrogenation)
ISOPROPYLAMINE
+
Reactant
(Alkylation of primary amines)
Reactant
+
CID 5475562
(Chan-Lam coupling reaction)
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