| Weight | 407.901 g/mol |
|---|---|
| Formula | C23H22ClN3O2 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 6 |
Pagoclone (133737-32-3, 133737-48-1)
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- An efficient and cost-effective synthesis of pagoclone (Organic Process Research & Development, 2003)
- Exploratory randomized clinical study of pagoclone in persistent developmental stuttering: the EXamining Pagoclone for peRsistent dEvelopmental Stuttering Study. (Journal of Clinical Psychopharmacology, 2010)
- Crossover trial of pagoclone and placebo in patients with DSM-IV panic disorder (Journal of Psychopharmacology, 2001)
- A proof-of-concept study using [11C]flumazenil PET to demonstrate that pagoclone is a partial agonist (Psychopharmacology, 2005)
- The in vivo properties of pagoclone in rat are most likely mediated by 5#-hydroxy pagoclone (Neuropharmacology, 2006)
- Evaluation of the abuse potential of pagoclone, a partial GABAA agonist. (Journal of Clinical Psychopharmacology, 2006)
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Predict GHS Hazards for Any Chemical in silico.
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SMILESCC(C)CCC(=O)CC1C2=CC=CC=C2C(=O)N1C3=NC4=C(C=C3)C=CC(=N4)Cl
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InChIKeyHIUPRQPBWVEQJJ-UHFFFAOYSA-N
- Pubchem - Pagoclone
- Wikipedia - pagoclone
Pagoclone is an anxiolytic agent from the cyclopyrrolone family, related to better-known drugs such as the sleeping medication zopiclone. It was synthesized by a French team working for Rhone-Poulenc & Rorer S.A. Pagoclone belongs to the class of nonbenzodiazepines, which have similar effects to the older benzodiazepine group, but with quite different chemical structures.
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