| Weight | 314.498 g/mol |
|---|---|
| Formula | C19H26N2S |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 4 |
pergolide (66104-22-1)
Score:
#82 in Neurology
,
#421 in Neuroscience
,
#1923 in Biology
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- Treatment of Parkinson's disease with pergolide and relation to restrictive valvular heart disease (The Lancet, 2004)
- Valvular Heart Disease in Patients Taking Pergolide (Mayo Clinic Proceedings, 2002)
- A randomized controlled study of pergolide in patients with restless legs syndrome (Neurology, 1999)
- Pramipexole and pergolide in the treatment of depression in Parkinson's disease:a national multicentre prospective randomized study. (European Journal of Neurology, 2003)
- A multicenter double-blind placebo-controlled trial of pergolide as an adjunct to sinemet in Parkinson's disease (Movement Disorders, 1994)
- Pergolide and carbidopa/levodopa treatment of the restless legs syndrome and periodic leg movements in sleep in a consecutive series of patients (Sleep, 1996)
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Predict GHS Hazards for Any Chemical in silico.
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SMILESCCCN1CC(CC2C1CC3=CNC4=CC=CC2=C34)CSC
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InChIKeyYEHCICAEULNIGD-UHFFFAOYSA-N
- Pubchem - pergolide
- Wikipedia - pergolide
Pergolide (trade names Permax, Prascend) is an ergoline-based dopamine receptor agonist used in some countries for the treatment of Parkinson's disease (PD). PD is associated with reduced dopamine activity in the substantia nigra of the brain. Pergolide acts on many of the same receptors as dopamine to increase receptor activity.
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