| Weight | 178.191 g/mol |
|---|---|
| Formula | C9H10N2O2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 2 |
phenacemide (63-98-9)
(phenylacetyl)urea · phenuron
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- Phenacemide in treatment of epilepsy. (JAMA, 1951)
- Ethylphenacemide and phenacemide: conformational similarities to diphenylhydantoin and stereochemical basis of anticonvulsant activity. (Proceedings of the National Academy of Sciences of the United States of America, 1977)
- Rise in serum and urine creatinine after phenacemide (Clinical Pharmacology & Therapeutics, 1978)
- USE OF PHENACEMIDE (PHENURONE) IN TREATMENT OF NARCOLEPSY AND CATAPLEXY: A Preliminary Report (Journal of Nervous and Mental Disease, 1953)
- Use of phenacemide in epilepsy, with analysis of fatal reactions and case report. (JAMA, 1955)
- Phenacemide in the treatment of epilepsy: results of treatment of 411 patients and review of the literature. (The New England Journal of Medicine, 1957)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - (phenylacetyl)urea
- phenuron
-
SMILESC1=CC=C(C=C1)CC(=O)NC(=O)N
-
InChIKeyXPFRXWCVYUEORT-UHFFFAOYSA-N
- Pubchem - phenacemide
- Wikipedia - phenacemide
Phenacemide (INN, BAN) (brand name Phenurone), also known as phenylacetylurea, is an anticonvulsant of the ureide (acetylurea) class. It is a congener and ring-opened analogue of phenytoin (a hydantoin), and is structurally related to the barbiturates and to other hydantoins. Phenacemide was introduced in 1949 for the treatment of epilepsy, but was eventually withdrawn due to toxicity.
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