| Weight | 252.273 g/mol |
|---|---|
| Formula | C15H12N2O2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 2 |
Phenytoin (57-41-0, 630-93-3)
Dilantin · Diphenylhydantoin · Phenytoin Sodium
Score:
#2 in Neurology
,
#23 in Neuroscience
,
#138 in Biology
,
#144 in Chemistry
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- Sigma-Aldrich - Phenytoin33.10 - 338.10 USD
- Fisher Scientific - Search for Phenytoin
- TCI - Phenytoin19.00 - 164.00 USD
- Letter: Optimum phenytoin-dosage regimens. (The Lancet, 1976)
- Comparison of Carbamazepine, Phenobarbital, Phenytoin, and Primidone in Partial and Secondarily Generalized TonicClonic Seizures (The New England Journal of Medicine, 1985)
- A randomized, double-blind study of phenytoin for the prevention of post-traumatic seizures. (The New England Journal of Medicine, 1990)
- A comparison of magnesium sulfate with phenytoin for the prevention of eclampsia (The New England Journal of Medicine, 1995)
- Phenobarbital compared with phenytoin for the treatment of neonatal seizures. (The New England Journal of Medicine, 1999)
- Phenytoin prevents stress and corticosteroneinduced atrophy of CA3 pyramidal neurons (Hippocampus, 1992)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H302: Harmful if swallowed
Warning Acute toxicity, oral - Category 4 - H351: Suspected of causing cancer
Warning Carcinogenicity - Category 2 - H370: Causes damage to organs
Danger Specific target organ toxicity, single exposure - Category 1 - Dilantin
- Diphenylhydantoin
- Phenytoin Sodium
- Epanutin
- Sodium Diphenylhydantoinate
- Epamin
- Hydantol
- Dihydan
- Antisacer
- Park Davis brand of Phenytoin
- Pfizer Brand of Phenytoin
- 5,5-Diphenylhydantoin
- Phizer Brand of Phenytoin
- Difenin
- Phenytoin Phizer Brand
- Phenytoin Pfizer Brand
- Fenitoin
-
SMILESC1=CC=C(C=C1)C2(C(=O)NC(=O)N2)C3=CC=CC=C3
-
InChIKeyCXOFVDLJLONNDW-UHFFFAOYSA-N
- Pubchem - Phenytoin
- Wikipedia - phenytoin
Phenytoin (PHT), sold under the brand name Dilantin among others, is an anti-seizure medication. It is useful for the prevention of tonic-clonic seizures and partial seizures, but not absence seizures. The intravenous form is used for status epilepticus that does not improve with benzodiazepines.
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Most-cited Publications
Areas of Application
Safety
Trends
Alternate Names
Estimated Properties
| Boiling Point | 370.83 C | EPA T.E.S.T. |
|---|---|---|
| Density | 1.31 g/cm3 | EPA T.E.S.T. |
| Flash Point | 202.03 C | EPA T.E.S.T. |
| Water Solubility | 164.46 mg/L | EPA T.E.S.T. |
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Synthesis
Reactant
+
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Phenytoin
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