Weight | 375.488 g/mol |
---|---|
Formula | C21H30FN3O2 |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 1 |
Aromatic Rings | 1 |
Rotatable Bonds | 7 |
Pipamperone (1893-33-0)
R 3345 · Dipiperon · 1'-(3-(4-fluorobenzoyl)propyl)-(1,4'-bipiperidine) -4'-carboxamide
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- Intracranial self-stimulation in rats as a function of various stimulus parameters: II. Influence of haloperidol, pimozide and pipamperone on medial forebrain bundle stimulation with monopolar electrodes (Psychopharmacology, 1972)
- Sleep disorders in patients with severe mental depression: double-blind placebo-controlled evaluation of the value of pipamperone (Dipiperon). (Acta Psychiatrica Scandinavica, 1977)
- CHLORDIAZEPOXIDE, DIPIPERON AND AMOBARBITAL. DOSE EFFECT STUDIES ON HUMAN BEINGS. (Psychopharmacology, 1963)
- Is it possible to predict the clinical effects of neuroleptics from animal data? Part V: From haloperidol and pipamperone to risperidone. (Drug Research, 1994)
- PIPAMPERONE (DIPIPERON, R 3345) IN TROUBLESOME MENTAL RETARDATES: A DOUBLE-BLIND PLACEBO CONTROLLED CROSS-OVER STUDY WITH LONG-TERM FOLLOW-UP (Acta Psychiatrica Scandinavica, 1975)
- Different regulation of rat 5-HT2A and rat 5-HT2C receptors in NIH 3T3 cells upon exposure to 5-HT and pipamperone (European Journal of Pharmacology, 2001)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - R 3345
- Dipiperon
- 1'-(3-(4-fluorobenzoyl)propyl)-(1,4'-bipiperidine) -4'-carboxamide
- Pipamperon-neuraxpharm
- pipamperone dihydrochloride
-
SMILESC1CCN(CC1)C2(CCN(CC2)CCCC(=O)C3=CC=C(C=C3)F)C(=O)N
-
InChIKeyAXKPFOAXAHJUAG-UHFFFAOYSA-N
- Pubchem - Pipamperone
- Wikipedia - pipamperone
Pipamperone (INN, USAN, BAN), also known as carpiperone and floropipamide or fluoropipamide, and as floropipamide hydrochloride (JAN), is a typical antipsychotic of the butyrophenone family used in the treatment of schizophrenia. It is or has been marketed under brand names including Dipiperon, Dipiperal, Piperonil, Piperonyl, and Propitan. Pipamperone was discovered at Janssen Pharmaceutica in 1961, and entered clinical trials in the United States in 1963.
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